The purpose of the study was to identify the structural and morphological characteristics of myocardium in patients with chronic renal insufficiency with clinical signs of heart failure and coronary heart disease. Surveyed 141 patients with chronic renal insufficiency 0, I, II, III stages. An eсhocardioscopiс study were held on the Vivid S6, General Electric, United States, which was of course-diastolic left ventricular cavity transverse dimension, thickness of the ventricular septal and posterior wall of the left ventricle, the length of the left ventricle in diastolic phase. Calculation is made of left ventricular myocardial mass index, index of the sphericity of the eccentricity. Determined the content of creatinine, CK-MB, troponin I and myoglobin. Morphological study on myocardial autopsic material 46 deaths of patients with chronic renal failure of varying degrees of severity. The Results. Initial displays remodeling appear in patients in the early stages of the disease. The loading phase of the disease is growing concentric hypertrophy of the left ventricle, there has been a progression of remodeling in increasing the frequency of occurrence of spherisation the cavity of the left ventricle. Dialysis reduces the severity of concentric hypertrophy of the left ventricle. As a result of the microscopic study of the heart was installed correlative dependence of structural changes in the myocardium of symptoms of chronic kidney failure.
сhronic renal failure, cardioscopie, myocardium, remodeling.
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