Moscow, Russian Federation
Moscow, Russian Federation
Moscow, Russian Federation
Moscow, Russian Federation
GRNTI 76.33 Гигиена и эпидемиология
GRNTI 76.03 Медико-биологические дисциплины
OKSO 31.06.2001 Клиническая медицина
OKSO 31.08.08 Радиология
OKSO 32.08.12 Эпидемиология
OKSO 14.04.02 Ядерные физика и технологии
BBK 534 Общая диагностика
BBK 51 Социальная гигиена и организация здравоохранения. Гигиена. Эпидемиология
TBK 5712 Медицинская биология. Гистология
TBK 5734 Медицинская радиология и рентгенология
TBK 6212 Радиоактивные элементы и изотопы. Радиохимия
TBK 5708 Гигиена и санитария. Эпидемиология. Медицинская экология
Colorectal cancers (CRC) takes the leading position in the incidence of morbidity and mortality worldwide. Metastatic CRC in the primary diagnosis ranges from 15 to 35 %. Lung metastasis are the most frequent extraperitoneal manifestation of the metastatic process. Such patients are relatively rare and there are no clear recommendations for their treatment tactics to date. This clinical case describes a successful strategy of using preoperative prolonged chemoradiotherapy on a primary tumor and stereotactic irradiation of lung metastasis, with courses of chemotherapy, with further radical laparoscopic operation, in a patient with disseminated primary multiple rectal cancer, synchronous sigmoid colon cancer and 2 metastatic focuses in both lungs.
rectal cancer, metastatic, lung metastasis, stereotactic body radiotherapy, ablative radiation therapy, chemoradiotherapy
1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, Rosso S. et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012; Eur J Cancer 2013;49(6):1374-403.
2. Goldberg RM. Advances in the treatment of metastatic colorectal cancer. Oncologist. 2005; 10 Suppl 3:40-8.
3. Zacharakis M, Xynos I.D, Lazaris A. et al. Predictors of survival in stage IV metastatic colorectal cancer. Anticancer Res. 2010;30(2):653-60.
4. Manfredi S, Lepage C, Hatem C, Coatmeur O. et al. Epidemiology and management of liver metastases from colorectal cancer. Ann Surg. 2006;244(2):254-9.
5. Nordholm-Carstensen A, Krarup PM, Jorgensen LN, Wille-Jorgensen PA, et al. On behalf of Danish colorectal Cancer group. Occurrence and survival of synchronous pulmonary metastases in colorectal cancer: a nationwide cohort study. Eur J Cancer. 2014; 50:447-56.
6. Mitry E, Guiu B, Cosconea S, Jooste V, et al. Epidemiology, management and prognosis of colorectal cancer with lung metastases: a 30-year population-based study. Gut. 2010; 59(10):1383-8.
7. Tan KK, Lopes Gde L. Jr, Sim R, et al. How uncommon are isolated lung metastases in colorectal cancer? A review from database of 754 patients over 4 years. J Gastrointest Surg. 2009; 13:642- 648.
8. Clark JW, Grothey A. Systemic chemotherapy for nonoperable metastatic colorectal cancer: treatment recommendations. https://www.uptodate.com/contents/systemic-chemotherapy-for-nonoperable-metastatic-colorectal-cancer-treatment-recommendations ?search=systemic-chemotherapy-for-nonoperable-metastatic-colorectal-cancer-treatment& source=search_result&selected Title=1~150&usage_type= default&display_rank=1 (This topic last updated: Jan 13, 2020).
9. Blalock A. Recent advances in surgery. N Engl J Med. 1944;231:261-7.
10. Pfannschmidt J, Dienemann H, Hoffmann H. Surgical resection of pulmonary metastases from colorectal cancer: a systematic review of published series. Ann Thorac Surg. 2007; 84:324-38.
11. Pastorino U, Buyse M, Friedel G, et al. Long-term results of lung metastasectomy: prognostic analyses based on 5206 cases. J Thorac Cardiovasc Surg. 1997; 113:37-49.
12. Timmerman RD, Bizekis CS, Pass HI, et al. Local surgical, ablative, and radiation treatment of metastases. CA Cancer J Clin. 2009;59 P145-70.
13. Gonzalez M, Ris H.B, Krueger T, Gervaz P. Colorectal cancer and thoracic surgeons: close encounters of the third kind. Expert RevAnticancer Ther. 2012;12:495-503.
14. Treasure T. Pulmonary metastasectomy for colorectal cancer: weak evidence and no randomised trials. Eur J Cardiothorac Surg. 2008;33P300-2.
15. Inoue M, Kotake Y, Nakagawa K, Fujiwara K, et al. Surgery for pulmonary metastases from colorectal carcinoma. Ann Thorac Surg. 2000;70:380-3.
16. McAfee MK, Allen MS, Trastek VF, Ilstrup DM, et al. Colorectal lung metastases: results of surgical excision. Ann Thorac Surg. 1992; 53:780-5.
17. Regnard JF, Grunenwald D, Spaggiari L, et al. Surgical treatment of hepatic and pulmonary metastases from colorectal cancers. Ann Thorac Surg. 1998; 66:214-8.
18. Sakamoto T, Tsubota N, Iwanaga K, Yuki T, et al:ulmonary resection for metastases from colorectal cancer. Chest. 2001; 119:1069-72.
19. Carballo M, Maish M.S, Jaroszewski D.E, Holmes C.E. Videoassisted thoracic surgery (VATS) as a safe alternative for the resection of pulmonary metastases: a retrospective cohort study. J Cardiothorac Surg. 2009; 4:13.
20. Chao YK, Chang HC, Wu YC, Liu Y.H, et al. Management of lung metastases from colorectal cancer: video-assisted thoracoscopic surgery versus thoracotomy-a casematched study. Thorac Cardiovasc Surg. 2012; 60:398-404.
21. Dong S, Zhang L, Li W, Du J, et al. Evaluation of videoassisted thoracoscopic surgery for pulmonary metastases: a metaanalysis. PLoS ONE. 2014; 9:329.
22. Nakajima J, Murakawa T, Fukami T, Takamoto S. Is thoracoscopic surgery justified to treat pulmonary metastasis from colorectal cancer?. Interact Cardiovasc Thorac Surg. 2008; 7:212-6.
23. Nakas A, Klimatsidas M.N, Entwisle J, Martin-Ucar A.E, et al. Video-assisted versus open pulmonary metastasectomy: the surgeon’s finger or the radiologist’s eye?. Eur J Cardiothorac Surg. 2009; 36:469-74
24. Ibrahim T, Tselikas L, Yazbeck C, Kattan J. Systemic versus local therapies for colorectal cancer pulmonary metastasis: what to choose and when?. J Gastrointest Cancer 2016; 47:223-31.
25. Van Cutsem E, Cervantes A, Adam R, et al. ESMO consensus guidelines for the management of patients with metastatic colorectal cancer. Ann Oncol 2016; 27:1386-422.
26. Hiraki T, Gobara H, Iguchi T, Fujiwara H, et al. Radiofrequency ablation as treatment for pulmonary metastasis of colorectal cancer. World J Gastroenterol. 2014; 20:988-96.
27. Legras A, Mordant P, Cazes A, Riquet M.. Radiofrequency of lung metastases: should initial pneumothorax predict treatment failure?. Rev Pneumol Clin. 2013; 69:336-9.
28. Matsui Y, Hiraki T, Gobara H, et al. Long-term survival following percutaneous radiofrequency ablation of colorectal lungmetastases. J Vasc Interv Radiol. 2015; 26:303-10.
29. Schneider T. Thermal ablation of malignant lung tumours. Zentralbl Chir. 2015;140:104-8.
30. Takahashi W, Nakajima M, Yamamoto N, et al. Carbon ion radiotherapy for oligo-recurrent lung metastases from colorectal cancer: a feasibility study. Radiat Oncol. 2014;9:68.
31. Yan TD, King J, Sjarif A, Glenn D, et al. Learning curve for percutaneous radiofrequency ablation of pulmonary metastases from colorectal carcinoma: a prospective study of 70 consecutive cases. Ann Surg Oncol. 2006;13:1588-95.
32. Yan TD, King J, Sjarif A, Glenn D, et al. Percutaneous radiofrequency ablation of pulmonary metastases from colorectal carcinoma: prognostic determinants for survival. Ann Surg Oncol. 2006; 13:1529-37.
33. Nahum Goldberg S, Dupuy D.E. Image-guided radiofrequency tumor ablation: challenges and opportunities-part I. J Vasc Interv Radiol. 2001;12:1021-32.
34. Hiraki T, Gobara H, Mimura H, et al. Radiofrequency ablation of lung cancer at Okayama University Hospital: a review of 10 years of experience. Acta Med Okayama. 2011; 65:287-97.
35. de Baere T, Tselikas L, Pearson E, et al. Interventional oncology for liver and lung metastases from colorectal cancer: the current state of the art. Diagn Interv Imaging. 2015;96:647-54.
36. Ferguson J, Alzahrani N, Zhao J, Glenn D, et al. Long term results of RFA to lung metastases from colorectal cancer in 157 patients. Eur J Surg Oncol. 2015;41:690-5
37. Chi A, Liao Z, Nguyen NP, Xu J, et al. Systemic review of the patterns of failure following stereotactic body radiation therapy in early-stage non-small-cell lung cancer: clinical implications. Radiother Oncol. 2010;94:1-11
38. Fuks Z, Kolesnick R. Engaging the vascular component of the tumor response. Cancer Cell. 2005;8:89-91
39. Carvajal C, Navarro-Martin A, Cacicedo J, Ramos R, et al. Stereotactic body radiotherapy for colorectal lung oligometastases: preliminary single institution results. J BUON. 2015;20:158-65.
40. Filippi AR, Badellino S, Ceccarelli M, et al. Stereotactic ablative radiation therapy as first local therapy for lung oligometastases from colorectal cancer: a single-institution cohort study. Int J Radiat Oncol Biol Phys. 2015;91:524-9
41. Takeda A, Sanuki N, Kunieda E. Role of stereotactic body radiotherapy for oligometastasis from colorectal cancer. World J Gastroenterol. 2014;20:4220-9
42. Rusthoven KE, Kavanagh BD, Burri SH, et al. Multiinstitutional phase I/II trial of stereotactic body radiation therapy for lung metastases. J Clin Oncol. 2009;27:1579-84
43. Widder J, Klinkenberg TJ, Ubbels JF, Wiegman E.M, et al. Pulmonary oligometastases: metastasectomy or stereotactic ablative radiotherapy?. Radiother Oncol. 2013;107:409-13
44. Schlijper RC, Grutters JP, Houben R, et al. What to choose as radical local treatment for lung metastases from colo-rectal cancer: surgery or radiofrequency ablation?. Cancer Treat Rev. 2014;40:60-7.