GASTROINTESTINAL STROMAL TUMORS (GIST): DIAGNOSIS AND TREATMENT
Rubrics: ONCOLOGY
Authors:
1.
Chita, Chita, Russian Federation
2.
Chita, Chita, Russian Federation
3.
Chita, Chita, Russian Federation
4.
Chita, Chita, Russian Federation
5.
Chita, Chita, Russian Federation
6.
Chita, Chita, Russian Federation
Type:
Article
Pages:
from 52
to 58
Status:
Published
Received:
14.11.2017
Accepted:
30.11.2017
Published:
30.11.2017
Subject area:
UDK 61 Медицина. Охрана здоровья
Language:
Russian
Keywords:
opuhol', diagnostika, hirurgiya, lechenie
Abstract (English):
Predstavlen analiz diagnostiki i lecheniya 67 bol'nyh so stromal'nymi opuholyami zheludochno-kishechnogo trakta po materialam dvuh klinik i Zabaykal'skogo kraevogo patologo-anatomicheskogo byuro. U 8 chelovek opuhol' lokalizovalas' v pischevode, u 43 – v zheludke, u 3 – v dvenadcatiperstnoy kishke, u 2 – v toschey kishke, u 8 – v obodochnoy kishke, u 3 – v pryamoy kishke. Opuhol' oslozhnilas' zheludochno-kishechnym krovotecheniem u 31 pacienta, u 3 pacientov ono bylo fatal'nym. Bol'shinstvo (58 chelovek) pacientov operirovany s primeneniem organosohranyayuschih metodik bez limfadenektomii. Posle operacii umer 1 pacient v otdalennom periode. Targetnaya terapiya ingibitorami tirozinkinaz ispol'zovana u 2 bol'nyh. Pri gistologicheskom issledovanii opuholey smeshannyy variant vstretilsya v 6 nablyudeniyah, v ostal'nyh sluchayah primerno v ravnom sootnoshenii vstrechalis' veretenokletochnyy i epitelioidnokletochnyy varianty. Privedeny chetyre naibolee pokazatel'nyh nablyudeniya lecheniya pri lokalizacii opuholi v verhnih otdelah zheludochno-kishechnogo trakta. Nashi nablyudeniya svidetel'stvuyut o tom, chto krovotechenie iz opuholi – eto naibolee chastoe oslozhnenie, svoystvennoe gastrointestinal'nym stromal'nym opuholyam (GISO). Ekzoorgannyy rost opuholi, osobenno zheludochnoy lokalizacii, neredko privodit k oshibkam v diagnostike, kogda GISO prinimayut za psevdokistu podzheludochnoy zhelezy.
Predstavlen analiz diagnostiki i lecheniya 67 bol'nyh so stromal'nymi opuholyami zheludochno-kishechnogo trakta po materialam dvuh klinik i Zabaykal'skogo kraevogo patologo-anatomicheskogo byuro. U 8 chelovek opuhol' lokalizovalas' v pischevode, u 43 – v zheludke, u 3 – v dvenadcatiperstnoy kishke, u 2 – v toschey kishke, u 8 – v obodochnoy kishke, u 3 – v pryamoy kishke. Opuhol' oslozhnilas' zheludochno-kishechnym krovotecheniem u 31 pacienta, u 3 pacientov ono bylo fatal'nym. Bol'shinstvo (58 chelovek) pacientov operirovany s primeneniem organosohranyayuschih metodik bez limfadenektomii. Posle operacii umer 1 pacient v otdalennom periode. Targetnaya terapiya ingibitorami tirozinkinaz ispol'zovana u 2 bol'nyh. Pri gistologicheskom issledovanii opuholey smeshannyy variant vstretilsya v 6 nablyudeniyah, v ostal'nyh sluchayah primerno v ravnom sootnoshenii vstrechalis' veretenokletochnyy i epitelioidnokletochnyy varianty. Privedeny chetyre naibolee pokazatel'nyh nablyudeniya lecheniya pri lokalizacii opuholi v verhnih otdelah zheludochno-kishechnogo trakta. Nashi nablyudeniya svidetel'stvuyut o tom, chto krovotechenie iz opuholi – eto naibolee chastoe oslozhnenie, svoystvennoe gastrointestinal'nym stromal'nym opuholyam (GISO). Ekzoorgannyy rost opuholi, osobenno zheludochnoy lokalizacii, neredko privodit k oshibkam v diagnostike, kogda GISO prinimayut za psevdokistu podzheludochnoy zhelezy.
Keywords:
opuhol', diagnostika, hirurgiya, lechenie
opuhol', diagnostika, hirurgiya, lechenie
1. Stromal'nye opuholi zheludochno-kishechnogo trakta
