CHARACTERISTIC OF MULTIDRAG RESISTANCE IN TUBERKULOSIS PATIENTS IN SEPARATE TERRITORIES OF IRKUTSK REGION
Abstract and keywords
Abstract (English):
The prevalence of multi-drug resistance (MDR) in separate territories of the Irkutsk region is different, which is as-sociated with the geographical features and the availability of microbiological research facilities. Between 2003 and 2015, the proportion of new TB cases with MDR increased in most of the territories of the region except “Large Cities” and the Buryat national district. In Large Cities of Irkutsk region and Buryat district MDR level is high, but the growth rate is insignificant. The area of “Major settlements along the railway” was characterized by an intensive increase in the proportion of first-time detected and previously treated TB patients with MDR. One reason for this phenomenon is the intense migration of the population. In “Northern areas” there was an accumulation of MDR among contingents associated with the empirical assignment of anti-TB drugs and low availability of microbiological testing. In the “Rural areas” MDR was rarely identified due to troubles with microbiological diagnostics.

Keywords:
multidrugresistance, tuberculosis
References

1. BorovitskiyVS (2012). Fibro-cavernous pulmonary tuberculosis. Penitentiary aspects [Fibrozno-kavernoznyy tuberkulez legkikh. Penitentsiarnye aspekty]. Tuberkulez i bolezni legkikh, (9), 3-15.

2. Kazenniy BY, KiselevaYY, IkonnikovaTV (2014).Approach to the treatment of patients with tuberculosis with multidrug resistance of the pathogen in the Orel region [Podkhod k lecheniyu patsientov s tuberkulezom s mnozhestvennoy lekarstvennoy ustoychivost’yu vozbuditelya v Orlovskoy oblasti]. Tuberkulez i bolezni legkikh. (1), 14-21

3. KapkovLP (2014). Why are there more TB patients with multi-drug resistant pathogen? [Pochemu bol’nykh tuberkulezom s mnozhestvennoy lekarstvennoy ustoychivost’yu vozbuditelya stanovitsya bol’she?]. Tuberkulez i bolezni legkih. (11), 11-17.

4. MarkelovYM, MarjandyshevAO (2013). Role of amplification of drug resistance in the formation of acquired multidrug resistance [Rol’ amplifikatsii lekarstvennoy ustoychivosti v formirovanii priobretennoy mnozhestvennoy lekarstvennoy ustoychivosti]. Tuberkulez i bolezni legkih. (7), 22-27.

5. PopovSA, PuzanovVA, SabgajdaTP (2011). Problems of monitoring of drug-resistant tuberculosis in the Russian Federation. The evaluation of the first cycle of monitoring [Problemy monitoringa tuberkuleza s lekarstvennoj ustojchivost’ju v Rossijskoj Federacii. Ocenka rezul’tatov pervogo cikla monitoringa]. Tuberkulez i bolezni legkih. (10), 16-21

6. UstjuzhaninaES, KibrikBS, SosninaOY (2011). Critically increasing chemoresistance of Mycobacterium tuberculosis and possible prospects of increase of efficiency of treatment of new cases of destructive pulmonary tuberculosis [Kriticheski narastajushhaja himiorezistentnost’ mikobakterij tuberkuleza i vozmozhnye perspektivy povyshenija jeffektivnosti lechenija vpervye vyjavlennyh bol’nyh destruktivnym tuberkulezom legkih]. Tuberkulez i bolezni legkih. (5), 196-197

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