Tula, Tula, Russian Federation
Russian Federation
Tula, Tula, Russian Federation
UDC 61
Idiopathic pulmonary hypertension (IPH) is a rare but severe disease characterized by increased pressure in the pulmonary artery without an obvious cause or in connection with other known diseases. This form of hypertension be-longs to group 1 of pulmonary hypertension according to the classification of the World Organization on Pulmonary Hypertension (WHO) and is characterized by a severe clinical picture, progressive course and high mortality rate. The relevance of studying IPH is determined by the need for early diagnosis and the de-velopment of effective treatment methods, since this disease significantly worsens the quality of life of patients and leads to complications from the cardiovascular system.
idiopathic pulmonary hypertension, dyspnea, right ventricular failure, endotheli-al dysfunction, pulmonary vascular remodeling.
1. Gali N., Gumbert M., Vachieri Zh.-L. i dr. Rukovodstvo ESC/ERS po diagnostike i lecheniyu legochnoy gipertenzii, 2022 // Evropeyskiy kar-diologicheskiy zhurnal. 2022. T. 43, № 24. S. 3618-3731.
2. Chazova I.E., Martynyuk T.V., Shmal'c A.A. i dr. Evraziyskie rekomendacii po diagnostike i lecheniyu legochnoy gipertenzii (2023) // Evraziyskiy kardiologicheskiy zhurnal. 2024. № 1. S. 6-85. DOI:https://doi.org/10.38109/2225-1685-2024-1-6-85
3. Frost A., Badesch D., Simon J.R. et al. Diagnosis of pulmonary hy-pertension // European Respiratory Journal. 2019. Vol. 53. P. 1801904.
4. Avdeev S.N., Barbarash O.L., Bautin A.E. i dr. Legochnaya giper-tenziya, v tom chisle hronicheskaya tromboembolicheskaya legochnaya gipertenziya: klinicheskie rekomendacii 2020 // Rossiyskiy kardiologicheskiy zhurnal. 2021. T. 26, № 12. S. 4683.
5. Humbert M., Sitbon O., Chaouat A. et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era // Circulation. 2010. Vol. 122, № 2. P. 156-163.
6. Hoeper M.M., Huscher D., Ghofrani H.A. et al. Elderly patients di-agnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA registry // International Journal of Cardiology. 2013. Vol. 168, № 2. P. 871-880.
7. Martynyuk T.V. Legochnaya gipertenziya: diagnostika i lechenie. M.: FGBU «NMIC kardiologii» Minzdrava Rossii, 2018. 208 s. ISBN 978-5-6040008-0-9
8. Chazova I.E., Martynyuk T.V. Legochnaya gipertenziya. M.: Prakti-ka, 2015. 928 s.
9. Alokova F.H., Blinova E.V., Sahnova T.A. i dr. Izmeneniya elek-trokardiogrammy v 12 otvedeniyah u bol'nyh s idiopaticheskoy legochnoy gipertenziey // Medicinskiy alfavit. 2018. № 4(36). S. 29-35.
10. Tongers J., Schwerdtfeger B., Klein G. et al. Incidence and clinical relevance of supraventricular tachyarrhythmias in pulmonary hypertension // American Heart Journal. 2007. Vol. 153. P. 127-132. DOI:https://doi.org/10.1016/j.ahj.2006.09.008
11. Remy-Jardin M., Ryerson C.J., Schiebler M.L. et al. Imaging of pul-monary hypertension in adults: a position paper from the Fleischner Society // European Respiratory Journal. 2021. Vol. 57. P. 2004455. DOI:https://doi.org/10.1183/13993003.04455-2020
12. Korobkova I.Z., Lazutkina V.K., Nizovcova L.A., Riden T.V. Metodicheskie aspekty rentgenologicheskoy ocenki legochnoy giperten-zii // Voprosy rentgenologii. 2015. № 4. S. 45-53. DOI:https://doi.org/10.20862/0042-4676-2015-0-4-14-2
13. Berger M., Haimowitz A., Van Tosh A. et al. Quantitative assess-ment of pulmonary hypertension in patients with tricuspid regurgitation using continuous wave Doppler ultrasound // Journal of the American College of Car-diology. 1985. Vol. 6, № 2. P. 359-365. DOI:https://doi.org/10.1016/s0735-1097(85)80172-8
14. Swift A.J., Dwivedi K., Johns C. et al. Diagnostic accuracy of CT pulmonary angiography in suspected pulmonary hypertension // European Radi-ology. 2020. Vol. 30. P. 4918-4929. DOI:https://doi.org/10.1007/s00330-020-06846-1
15. Chazova I.E., Martynyuk T.V., Valieva Z.S. i dr. Clinical and In-strumental Characteristics of Newly Diagnosed Patients with Various Forms of Pulmonary Hypertension according to the Russian National Registry // BioMed Research International. 2020. P. 6836973. PMID: 32626754. DOI:https://doi.org/10.1155/2020/6836973
16. Grunig E., MacKenzie A., Peacock A.J. et al. Standardized exercise training is feasible, safe, and effective in pulmonary arterial and chronic throm-boembolic pulmonary hypertension: results from a large European multicentre randomized controlled trial // European Heart Journal. 2021. Vol. 42. P. 2284-2295. DOI:https://doi.org/10.1093/eurheartj/ehaa696
17. Diagnostika i lechenie serdechno-sosudistyh zabolevaniy pri be-remennosti 2018: nacional'nye rekomendacii // Rossiyskiy kardiologiche-skiy zhurnal. 2018. № 3(155). S. 91-134. DOI:https://doi.org/10.15829/1560-4071-2018-3-91-134
