In this article the authors examine changes in the levels of tumor necrosis factor alpha and nitric oxide in the blood in patients with atrial fibrillation and hypertension. The study included 66 patients aged 60 to 75 years compared with the control group of 25 people. The results suggest that endothelial dysfunction is developed in patients. It is manifested by changes in the levels of tumor necrosis factor alpha and nitric oxide in the blood. The studied parameters can be the markers of severity and indicate a differentiated approach to various forms of atrial fibrillation. On the severity, an atrial fibrillation is clinically subdivided into paroxysmal, persis-tent and permanent (up to 30, 60 and 80 points, respectively).
atrial fibrillation, cytokines, nitric oxide, endothelial dysfunction, medico-social examination in points.
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