Currently, the methods of early diagnosis and treatment of stable angina are of interest to researchers. One of the methods of diagnosis is echocardiography using a two-dimensional speckle tracking. Technology speckle tracking allows to evaluate systolic and diastolic heart function in various cardiovascular diseases, including coronary heart disease (CHD). By means of this program all types of myocardial deformation: radial, circular, longitudinal, the rate of deformation and rotation of the myocardium can be evaluated. The clinical studies have shown that changes in the indices of deformation are sensitive markers of myocardial ischemia in the early stages [9]. In this study the authors investigated the effect of anti-anginal drug Coronater on the parameters of radial, circular and longitudinal deformation of the left ventricular myocardium in patients with angina pectoris 1-2 functional class (FC). The drug Coronater is phytotherapeutic preparation of anti-anginal action used to treat angina FC 1-2. The main active ingredients are Ligustikum Sichuan and broneol. Most clinical studies confirm the effectiveness of anti-anginal drug Coronater having significant coronarolytic and anti-ischemic effects.
coronary heart disease, two dimensional speckle tracking echocardiography, myocardial strain, longitudinal deformation, stable angina pectoris.
1. Pavlyukova E.N. Deformatsiya, rotatsiya i povorot levogo zheludochka po osi u bol´nykh ishemiche-skoy bolezn´yu serdtsa i tyazheloy levozheludochkovoy disfunktsiey. Patologiya krovoobrashcheniya i kar-diokhirurgiya, 2010.
2. Vasyuk Yu.A., Kopeleva M.V., Khadzegova A.B. Otsenka lokal´noy sokratimosti miokarda levogo zheludochka metodom tkanevoy doplerografii u patsientov s razlichnymi formami IBS. Med. zhurnal «SonoAce-Ultrasound», 2008. №17.
3. Alekhin M.N. Ul´trazvukovye metody otsenki deformatsii miokarda i ikh klinicheskoe znache-nie. Moskva: iz dom Vidar-M; 2012. 88 s.
4. Tor Biering - Sorensen, Soren Hoffman, Rasmus Mogelvang. Myocardial Strain Analysis by 2-Dimensional Speckle Tracking Echocardiography Improves Diagnostics of Coronary Artery Stenosis in Stable Angina Pectoris. Circ Cardiovasc Imaging. 2014. №7. R. 58-65.
5. Abduch M.C., Alencar A.M., Mathias Jr.W., Vieira M.L. Cardiac Mechanics Evaluated by Speckle Tracking Echocardiography. Arq Bras. Cardiol. 2014. V. 25.
6. Hoffmann S., Jensen J.S., Iversen A.Z., Soqaard P., Galatius S., Olsen N.T., Bech J. Tissue Doppler echocardiography improves the diagnosis of coronary artery stenosis in stable angine pectoris. Eur Heart J car-diovasc imaging. 2012. 13(9). R. 724-729.
7. Anwar A.M. Accuracy of two-dimensional speckle tracking echocardiography for the detection of significant coronary stenosis. J Cardiovasc. Ultrasound. 2013. 21(4). R. 177-182.
8. Khadartsev A.A., Zilov V.G., Oleynikova M.M., Naumova E.M. Koronatera v lechenii bol´nykh ishemicheskoy bolezn´yu serdtsa. Metodicheskoe posobie. Tula, 2003.
9. Abduch M.C., Alencar A.M., Mathias Jr.W., Vieira M.L. Cardiac Mechanics Evaluated by Speckle Tracking Echocardiography. Arq Bras. Cardiol. 2014. 25.
