Chelyabinsk, Russian Federation
GRNTI 76.33 Гигиена и эпидемиология
GRNTI 76.03 Медико-биологические дисциплины
OKSO 31.06.2001 Клиническая медицина
OKSO 31.08.08 Радиология
OKSO 32.08.12 Эпидемиология
OKSO 14.04.02 Ядерные физика и технологии
BBK 534 Общая диагностика
BBK 51 Социальная гигиена и организация здравоохранения. Гигиена. Эпидемиология
TBK 5712 Медицинская биология. Гистология
TBK 5734 Медицинская радиология и рентгенология
TBK 6212 Радиоактивные элементы и изотопы. Радиохимия
TBK 5708 Гигиена и санитария. Эпидемиология. Медицинская экология
Purpose: The analysis of the structure of malignant neoplasms (MN) incidence among the population in the city Ozyorsk, located near Mayak Production Association, based on the information from the territorial cancer registry. Materials and methods: There were 14681 first diagnosed cases of malignant neoplasms at the period from 1948 to 2016 in the territorial cancer registry of Ozyorsk. The diagnoses were verified by all available medical documents. The structure of MN incidence, vital status of diseased people, age in a year of diagnostics, rank distribution of the basic localizations were studied. Results: For 70 years period of follow-up there were 7676 cases from 14681 of MN incidence cases during the last 17 years (from 2000 to 2017) – as much as for the previous 51 years of follow-up from 1948 to 1999 (7005 cases). In the MN structure solid cancer constitutes 94.5 %, hemoblastoses – 5.5 %. As at December 31, 2016 23.3 % of the diseased people were alive, 75.2 % died from all causes, 1.5 % lost to follow-up. The cause of 80,6 % deaths was MN. Age in the year of diagnostics constitutes 61,7 years. 75.8 % diagnoses have morphological confirmation. During the entire period of follow-up first three places belong to lung cancer, gastric cancer and prostate cancer for males; breast cancer, gastric cancer and colon cancer for females in the MN structure. Conclusions: During the period from 1948 to 2016 the growth of the first diagnosed MN cases among the population of Ozyorsk was a result of the population doubling and a fourfold increase of the citizens over the age of 50. Developed and supported cancer registry allows to analyze and partially control oncological situation in the closed cities of Rosatom.
cancer-registry, Mayak PA, Ozyorsk, population, malignant neoplasm
1. A Review of Human Carcinogens. Part D: Radiation. Lyon, France: IARC, 2012. 363 p.
2. Publikaciya 103 Mezhdunarodnoy Komissii po radiacionnoy zaschite (MKRZ) / Pod red. Kiseleva M.F., Shandaly N.K. M.: Alana, 2009. 344 c.
3. Vazhenin A.V., Domozhirova A.S., Aksenova I.A. i dr. Epidemiologicheskie osobennosti onkologicheskoy situacii i pokazateli sostoyaniya onkologicheskoy pomoschi naseleniyu v Chelyabinskoy oblasti v 2018 godu. Statisticheskiy sbornik. Chelyabinsk: Chelyabinskiy oblastnoy klinicheskiy centr onkologii i yadernoy mediciny, 2018. 60 s.
4. Cancer Registration: Principles and Methods. Lyon, France: IARC, 1991. 169 p.
5. Zielinski J.M., Shilnikova N.S., Krewski D. Canadian National Dose Registry of Radiation Workers: Overview of Research from 1951 through 2007 // Int. J. Occup. Med. Environ Health. 2008. V.21, No. 4. P. 269-75.
6. Haylock R.G.E., Gillies M., Hunter N., et al. Cancer Mortality and Incidence Following External Occupational Radiation Exposure: an Update of the 3rd Analysis of the UK National Registry for Radiation Workers // British Journal of Cancer. 2018. V.119. P. 631-637.
7. Hunter N., Harrison J.D., Kuznetsova I.S., Labutina E.V. Solid Cancer Incidence other than Lung, Liver and Bone in Mayak Workers: 1948-2004 // Br. J. Cancer. 2013. V.109, No. 7. P. 1989-1996.
8. Labutina E.V., Kuznetsova I.S., Hunter N., et al. Radiation Risk of Malignant Neoplasms in Organs of Main Deposition for Plutonium in the Cohort of Mayak Workers with Regard to Histological Types // Health Phys. 2013. V.105, No. 2. P. 165-76.
9. Kuznetsova I.S., Labutina E.V., Hunter N. Radiation Risks of Leukemia, Lymphoma and Multiple Myeloma Incidence in the Mayak Cohort: 1948-2004 // PLoS ONE. 2016. V.11, No. 9. P. 1-14.
10. Novoselov V.N., Nosach Yu.F., Entyakov B.N. Atomnoe serdce Rossii. Chelyabinsk: Avtograf, 2014. 528 c.
11. Fomin E.P., Okatenko P.V., Koshurnikova N.A. Zabolevaemost' zlokachestvennymi g. novoobrazovaniyami naseleniya g. Ozerska za period s 1948 po 2005 gody // Medicinskaya radiologiya i radiacionnaya bezopasnost'. 2007. T.52, № 6. S. 29-34.
12. Tret'yakov F.D., Romanov S.A., Prischepova M.S., Ryzhov V.P. Demograficheskaya situaciya v g. Ozerske. Ozersk: Redakcionno-izdatel'skiy centr VRB, 2007. 32 s.
13. Zlokachestvennye novoobrazovaniya v Rossii. http://www.oncology.ru /service/statistics/malignant_tumors/.
14. Merkov A.M., Polyakov L.E. Sanitarnaya statistika. M.: Medicina, 1974. 384 s.
