STUDYING OF RADIATION SAFETY OF 188Re-LABELED MAA PREPARATION FOR TREATMENT OF RESISTANT SYNOVITIS
Rubrics: NUCLEAR MEDICINE
Authors:
1.
A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
2.
A.I. Burnasyan Federal Medical Biophysical Center of FMBA
(Head of Laboratory)
employee
Russian Federation
employee
Russian Federation
3.
Federal Center of Nuclear Medicine Projects Design and Development of FMBA Russia, Moscow, Russia
Type:
Article
Pages:
from 38
to 46
Status:
Published
Received:
26.04.2021
Accepted:
27.04.2021
Published:
27.04.2021
Language:
Russian
Keywords:
radiation safety, MAA 5-10 µm, rhenium-188, radiopharmaceutical preparation
Abstract (English):
The article is written about studying of radiation safety of 188Re-labeled microspheres of albumin preparation (hand mode) for treatment of resistant synovitis. The study material was a radiopharmaceutical based on albumin microspheres 5 –10 µm with rhenium-188 for treatment of resistant synovitis. The studying has led to conclusion the number of radiopharmaceutical portions prepared by one operator should not exceed 70 times a year, which will ensure that the main limits of equivalent doses to hands and skin with a reserve factor of 2 (250 μSv/h) are not exceeded. Protective equipment should be used to reduce doses to hands, as the most critical to operator's body part irradiation.
The article is written about studying of radiation safety of 188Re-labeled microspheres of albumin preparation (hand mode) for treatment of resistant synovitis. The study material was a radiopharmaceutical based on albumin microspheres 5 –10 µm with rhenium-188 for treatment of resistant synovitis. The studying has led to conclusion the number of radiopharmaceutical portions prepared by one operator should not exceed 70 times a year, which will ensure that the main limits of equivalent doses to hands and skin with a reserve factor of 2 (250 μSv/h) are not exceeded. Protective equipment should be used to reduce doses to hands, as the most critical to operator's body part irradiation.
Keywords:
radiation safety, MAA 5-10 µm, rhenium-188, radiopharmaceutical preparation
radiation safety, MAA 5-10 µm, rhenium-188, radiopharmaceutical preparation
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