Tula, Tula, Russian Federation
Rheumatoid arthritis, like any chronic non-infectious disease, requires constant pharmacological therapy and monitoring of treatment. To relieve exacerbation, maintain long-term remission and improve the quality of life of patients, basic anti-inflammatory drugs are used, which have passed many years of testing for efficacy and safety and are available for patients. But there is a group of drugs that have appeared relatively recently - genetically engineered biological drugs. At the moment, their use is somewhat limited due to the presence of a number of problems. With the accumulation of data on the study of the safety of genetically engineered drugs in the treatment of rheumatoid arthritis, it will be possible to solve many practical issues that arise in the attending physician during the supervision of patients.
rheumatoid arthritis, genetically engineered drugs, basic therapy.
1. Avdeeva A.S., Misiyuk A.S., Satybaldyev A.M. i dr. Analiz rezul'tatov terapii tofacitinibom v real'noy klinicheskoy praktike (po dannym Obscherossiyskogo registra bol'nyh artritom OREL). Nauchno-prakticheskaya revmatologiya. 2020;58(3):262-267.
2. Aronova E.S., Lukina G.V., Sigidin Ya.A. Perenosimost' infliksimaba u pacientov s revmatoidnym artritom v real'noy klinicheskoy praktike. Nauchno-prakticheskaya revmatologiya. 2020;58(1):31-36.
3. ARR. Klinicheskie rekomendacii po lecheniyu i diagnostike revmatoidnogo artrita. 2018. - 102 s.
4. Dzhon H. Klippel i dr., redaktory: per. s angl. pod red. Nasonova E.L. i dr. Revmaticheskie zabolevaniya. V 3 t. T II. Zabolevaniya kostey i sustavov: [rukovodstvo]. - M.: GEOTAR - Media, 2012. - 520 s.
5. Mazurov V.I., Belyaeva I.B., Trofimov E.A. i dr. Sravnitel'naya ocenka vliyaniya sinteticheskih bazisnyh protivovospalitel'nyh i genno-inzhenernyh biologicheskih preparatov na klinicheskoe techenie, skorost' razvitiya destruktivnyh izmeneniy i kachestvo zhizni bol'nyh revmatoidnym artritom. Sovremennaya revmatologiya. 2019;13(3):22-29.
6. Nasonov E.L., akademik RAMN, redaktor. Genno - inzhenernye biologicheskie preparaty v lechenii revmatoidnogo artrita. -M.: IMA-PRESS, 2013.- 552s.
7. Nasonov E.L., Karateev D.E, Chichasova N.V. Rekomendacii EULAR po lecheniyu revmatoidnogo artrita - 2013: obschaya harakteristika i diskussionnye problemy. Nauchno-prakticheskaya revmatologiya.2013;51(6):609-22.
8. Hlaboshina V.N., Amirdzhanova V.N. Genno-inzhenernye biologicheskie preparaty pri endoprotezirovanii sustavov u bol'nyh revmatoidnym artritom. Sovremennaya revmatologiya. 2014;(4):72-75.
9. Chichasova N.V., Nasonov E.L. Bezopasnost' primeneniya genno-inzhenernyh biologicheskih preparatov pri revmatoidnom. Sovremennaya revmatologiya. 2010;(1):46-58.
10. Chichasova N.V. Revmatoidnyy artrit: problemy lecheniya na sovremennom etape. Sovremennaya revmatologiya. 2018;12(4):65-70.