Russian Federation
Russian Federation
Russian Federation
Russian Federation
Russian Federation
Russian Federation
Russian Federation
GRNTI 76.03 Медико-биологические дисциплины
GRNTI 76.33 Гигиена и эпидемиология
OKSO 14.04.02 Ядерные физика и технологии
OKSO 31.06.2001 Клиническая медицина
OKSO 31.08.08 Радиология
OKSO 32.08.12 Эпидемиология
BBK 51 Социальная гигиена и организация здравоохранения. Гигиена. Эпидемиология
BBK 534 Общая диагностика
TBK 5708 Гигиена и санитария. Эпидемиология. Медицинская экология
TBK 5712 Медицинская биология. Гистология
TBK 5734 Медицинская радиология и рентгенология
TBK 6212 Радиоактивные элементы и изотопы. Радиохимия
Purpose: To assess the reproductive health of male staff in the main departments of the Kursk nuclear power plant (NPP). Material and methods: The fertility and health of newborns were investigated. Data on marital status of 626 men of the staff and data about 813 newborns in families of male staff were analyzed. In the control group the data on the health status of newborns and pregnant groups of the population of Kurchatov city was used. Sources of information on doses to the personnel were the forms of a single system for monitoring and recording individual doses of radiation № 1-DOS “Information on the doses to persons in the conditions of normal operation of technogenic sources of ionizing radiation”. Results: Total occupational doses to the end of the main reproductive period (20–40 years) did not exceed 210 mSv, which is significantly below the threshold for temporary sterility during long-term irradiation (400 mSv/year, ICRP). Cases of infertile marriages in the families of the men of the staff (0.17 %) are below the estimation of the frequency of male infertility in Russia (1–2 %). Infant health in families of male staff and in the control group had no differences. The frequency of birth of health children was 65.3 % in families of male staff and 66.0 % for the control group. Frequency of birth of children with malformations was 35.7±6.5 per 1,000 live births and statistically (p = 0.84) did not differ from the frequency in the control group (37.4±5.3 per 1,000 live births) and was below the level adopted by the ICRP to calculate the radiation genetic risk (60 per 1,000 live births). There were no differences influenced by mother factors (age, diseases and complications during pregnancy) on fetal development and newborn health in families of the staff and control group. According to the calculations, the total occupational doses to men before the conception of children for more than 98 % of cases did not exceed 100 mSv, i.e. it was below the doses (>100 mSv), for which the genetic effects were observed in the number of epidemiological studies. However, it should be noted that 25.6 % of childbirth were in families, where men were older than 30 years, i.e. at the age, which is not subject to the additional job restrictions under the planned increased exposure. Conclusions: The impact of occupational exposure on the reproductive health status of men staff of the Kursk NPP was not identified.
Kursk NPP, male staff, reproductive health, infertility, health status, newborn children
1. Radiation safety standards (RSS-99/2009): Public health regulations. Moscow: Federal Center of Hygiene and Epidemiology of Rospotrebnadzor. 2009. 100 p. (Russian)
2. ICRP Publication 103. Eds. Kiselev MF, Shandala NK. Moscow: PKF «Alana». 2009. 311 pp. (Russian)
3. Crow J.F. A comparison of fetal and infant death rates in progeny of radiologist. Amer J Roentgenol. 1955;73:467-71.
4. Sever LE, Gilbert ES, Hessol NA, McIntyre JM. A case-control study of congenital malformations and occupational exposure to low-level ionizing radiation. Amer J Epidemiol. 1988;127:226-42.
5. Parker L, Pearce MS, Dickinson HO, et al. Stillbirths among offspring of male radiation workers at Sellafield nuclear reprocessing plant. Lancet. 1999;354(9180):1407-14.
6. Stepanova EI, Skvarskaya EA Clinical-genetic and cytogenetic characteristics of children born to liquidator of the Chernobyl accident. Collection of research papers “Genetic consequences of emergency radiation situations”. Moscow: Publ. RUDN. 2002. P. 115-6. (Russian)
7. Petrushkina NP. Health of children (1-2 generation) of workers of the first atomic industry Production Association “Mayak” (clinical and epidemiological study). Moscow: Dr. Sc. Med. Diss. 2003. 371 pp. (Russian)
8. Lyaginskaya AM, Tukov AR, Osipov VA, et al. Congenital Malformation at Posterity of the Liquidators of the Consequences of Chernobyl Accident. Radiation biology. Radioecology. 2009;49(6):694-702. (Russian)
9. Tsovianov AG, Kosterev VV, Kyuchkov VV, et al. Information-analytical reference book “Doses to personnel of organizations and the population in the areas served by the FMBA of Russia and the Russian Ministry of Defense in 2010”. Moscow. 2012. 86 pp. (Russian)
10. Merkov AM, Polyakov LE. Sanitary statistics (manual for physicians). Moscow. Medicine. 1974. 384 pp. (Russian)
11. Lebedev SV. Infertility: real statistic. 2009. http://www.probirka.org/ zhenskoe-besplodie/306-besplstat.html (Russian)
12. Kerimova ZM. Intrauterine growth retardation. Principles of pregnancy. Moscow: Abstract of diss. to PhD Med. Sc. 2002. 25 pp. (Russian)