Novosibirsk Institute of Antioxidants (laboratoriya vodorastvorimyh antioksidantov, rukovoditel')
Novosibirsk, Novosibirsk, Russian Federation
V obzore obosnovana perspektivnost' sozdaniya vodorastvorimyh antioksidantov, obladayuschih odnovremenno antiradikal'noy i protivoperoksidnoy aktivnostyami. Pokazano, chto predstaviteli takih soedineniy – S-(3-(4-gidroksiaril)propil)tiosul'faty – obladayut bioantioksidantnymi, kardioprotektornymi, protivovospalitel'nymi i protivoopuholevymi svoystvami i mogut byt' ispol'zovany dlya korrekcii patologicheskih sostoyaniy, svyazannyh s razvitiem okislitel'nogo stressa.
fenol'nye antioksidanty, vodorastvorimye antioksidanty, polifunkcional'nye antioksidanty, bioantioksidanty, svobodnoradikal'nye patologii
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3. Kolesnikova OP, Kandalintseva NV, Prosenko AE (2006). The hydrophilic antioxidant tiosulfan as a potential immunostimulant [Gidrofil’nyj antioksidant tiosul’fan kak potencialnyj immunostimulyator]. Bioantioksidant: tezisy dokladov VII mezhdunarodnoy konferentsii, 156-157.
4. Kolpakov AR, Zenkov NK, Menshchikova EB, Prosenko AE, Kandalintseva NV (2002). Effect of antioxidant thiosulfane on the work of isolated rat heart [Vliyanie antioksidanta tiosul’fana na rabotu izolirovannogo serdca krysy]. Bioantioksidant: tezisy dokladov VI mezhdunarodnoy konferentsii, 278-280.
5. Menshchikova EB, Zenkov NK, Lankin VZ, Bondar IA, Trufakin VA (2008). Oxidative stress: Pathological states and diseases [Okislitel’nyy stress: Patologicheskie sostoyaniya i zabolevaniya], 284.
6. Menshchikova EB, Lankin VZ, Kandalintseva NV. (2012). Phenolic antioxidants in biology and medicine [Fenol’nye bioantioksidanty v biologii i meditsine], 496.
7. Popova OA, Sakharov AV, Makeyev AA, Prosenko AE, Kandalintseva NV (2013). The comparative characteristic of chondroprotective properties of water-soluble antioxidants Mexidol and TC-13 [Sravnitel’naya kharakteristika khondroprotektornykh svoystv vodorastvorimykh antioksidantov meksidol i TS-13]. Fundamental’nye issledovaniya, (10-1), 119-124.
8. Smolyakova VI, Plotnikov MB, Chernysheva GA, Ivanov IC, Prosenko AE, Kandalintseva NV (2010). Haemorheologic effects of thiophane when liver is damaged by carbon tetrachloride [Gemoreologicheskie effekty tiofana pri porazhenii pecheni tetrahlormetanom]. Eksperimental’naya klinicheskaya farmakologiya, 73 (8), 32-34.
9. Smolyakova VI, Plotnikov MB, Chernysheva GA, Ivanov IC, Prosenko AE, Kandalintseva NV (2010). Antioxidant effects of thiophan in experimental tetrachlorolmethane-induced hepatitis [Antioksidantnye effekty tiofana pri eksperimental’nom porazhenii pecheni tetrakhlormetanom]. Byulleten’ sibirskoy meditsiny, 9 (5), 98-101.
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11. Prosenko AE, Gross MA, Kandalintseva NV, Tolstikova TG, Sorokina IV (2012). Means for correction of cytotoxic effects of paraneoplastic processes and chemotherapy, having anticancer activity: Patent N 2447888 of the Russian Federation [Sredstvo dlya korrektsii tsitostaticheskikh effektov paraneoplasticheskikh protsessov i khimioterapii, obladayushchee protivoopukholevoy aktivnost’yu: patent № 2447888 Ros. Federatsiya].
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19. Kemeleva EA, Vasyunina EA, Sinitsina OI, Nevinskii GA, Khomchenko AS, Gross MA, Kandalintseva NV, Prosenko AE (2008). New promising antioxidants based on 2,6-dimethylphenol. Russian Journal of Bioorganic Chemistry, 34 (4), 499-509.
20. Lyakhovich VV, Vavilin VA, Zenkov NK, Menshchikova EB (2006). Active defense under oxidative stress. The antioxidant responsive element. Biochemistry (Moscow), 71 (9), 962-974.
21. Martinovich GG, Martinovich IV, Cherenkevich SN, Zenkov NK, Menshchikova EB, Kandalintseva NV (2015). Phenolic antioxidant TS-13 regulating are-driven genes induces tumor cell death by a mitochondria-dependent pathway. Biophysics, 60 (1), 94-100.
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23. Menshchikova EB, Zenkov NK, Weisman NY, Kandalintseva NV, Prosenko AE (2010). Effect of phenol inducing the antioxidant responsive element on drosophila melanogaster lifespan. Bulletin of Experimental Biology and Medicine, 150 (1), 65-67.
24. Menshchikova EB, Tkachev VO, Zenkov NK, Lemza AE, Sharkova TV, Kandalintseva NV (2013). Anti-inflammatory activity of TS-13, ARE-inducing phenol antioxidant. Bulletin of Experimental Biology and Medicine, 155 (3), 366-369.
25. Menshchikova EB, Zenkov NK, Tkachev VO, Lemza AE, Kandalintseva NV (2013). Protective effect of are-inducing phenol antioxidant TS-13 in chronic inflammation. Bulletin of Experimental Biology and Medicine, 155 (3), 330-334.
26. Menshchikova EB, Zenkov NK, Tkachev VO, Wisman NY, Kandalintseva NV (2012). Are-inducing phenol antioxidant TC-13 improves survival of drosophila melanogaster in oxidative stress. Bulletin of Experimental Biology and Medicine, 154 (2), 260-264.
27. Ovchinnikova LP, Rotskaya UN, Vasyunina EA, Sinitsina OI, Nevinskii GA, Kandalintseva NV, Prosenko AE (2009). Antioxidative activity of thiophane [bis(3-(3,5-di-tret-butyl-4- hydroxyphenyl)propyl)sulfide]. Russian Journal of Bioorganic Chemistry, 35 (3), 379-384.
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29. Plotnikov MB, Smol’yakova VI, Ivanov IS, Chernysheva GA, Prosenko AE, Kandalintseva NV (2010). Synthesis and antioxidant activity of 3,5-dimethyl-4-hydroxybenzylthiododecane. Pharmaceutical Chemistry Journal, 44 (4), 189-191.
30. Prosenko AE, Terakh EI, Gorokh EA, Nikulina VV, Grigorev IA (2003). Synthesis and research of antioxidant properties of bis-(ω-(3,5-dialkyl-4-hydroxyphenyl)alkyl) sulfides). Russian Journal of Applied Chemistry, 76 (2), 248-252.
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33. Weisman NY, Men’shchikova EB, Zenkov NK, Kandalintseva NV, Golubovsky MD (2012). Effect of phenol inducing antioxidant responsive element on D. melanogaster lifespan. Advances in Gerontology, 2 (3), 221-229.
34. Zenkov NK, Menshchikova EB, Kandalintseva NV, Oleynik AS, Prosenko AE, Gusachenko ON, Shklyaeva OA, Vavilin VA, Lyakhovich VV (2007). Antioxidant and antiinflammatory activity of new water-soluble sulfur-containing phenolic compounds. Biochemistry (Moscow), 72 (6), 644-651.
