Tomsk, Tomsk, Russian Federation
Tomsk, Tomsk, Russian Federation
Issledovali rol' aktivnyh form kisloroda v signal'nom mehanizme rannego gipoksicheskogo prekondicionirovaniya ( rGP) in vivo. Ustanovili, chto predvaritel'noe vvedenie neselektivnogo antioksidanta nepryamogo deystviya N-(2-merkaptopropionil)-glicina i «lovushki» gidroksil'nyh radikalov 1,3-dimetiltiomocheviny polnost'yu ustranyalo infarkt-limitiruyuschiy effekt adaptacii. Vvedenie antioksidantov tempol i troloks, a takzhe primenenie N-(2-merkaptopropionil)-glicina posle rGP ne okazyvalo vliyaniya na zaschitnyy effekt adaptacii.
aktivnye formy kisloroda, prekondicionirovanie, gipoksiya, ishemiya, serdce
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