The article provides the review of domestic and foreign literature on the use of the Ex-Press drainage device in patients with refractory and primary open-angle glaucoma. We conducted a detailed analysis of hypotensive effectiveness of Ex-Press implantation combined with anti-VEGF drugs, antimetabolites (5-Fluorouracil, Mitomycin C), Glautex and Ologen drainages. We described the results of drainage device usage for neovascular, aphakic, pseudophakic glaucoma. We determined indications, modified methods of Ex-Press implantation and best options of combinations with drainages; established safe conditions of magnetic resonance imaging in patients with the implanted device. We presented all possible com-plications both in the early and late postoperative period. The influence of Ex-Press on endothelial layer of the cornea in dynamics was shown. On the basis of literature review it can be noted that Ex-press drainage device has proved to have a long hypotensive effect in patients with POAG and pseudophakia. Whereas in refractory glaucoma it requires a combination with drainage and anti-metabolites. Implantation of Ex-press requires dynamic monitoring of patients due to the risk of long-term postoperative complications.
Ex-Press, primary open-angle and refractory glaucoma
1. AbsalyamovMS, ZainullinaNB, MannanovaRF (2012). The results of the application of mini-shunt Ex-Press glaucoma surgery [Rezul’taty primeneniya mini-shunta Ex-Press v khirurgii glaukomy]. Vostok-Zapad: Sbornik nauchnykh trudov, 161-163
2. AvetisovSE, ErichevVP, AsratyanGK, AvetisovKS,KobzovaMV (2013). Microshunting in glaucoma surgery in pseudophakic eyes [Mikroshuntirovanie v khirurgii glaukomy v artifakichnykh glazakh]. Glaukoma, (3), 44-47.
3. AngelsBD (2013). First results in patients of advanced stages of open-angle glaucoma after one stage surgery with implantation of two different implants Ex-press and Ologen [Pervye rezul’taty u patsientov prodvinutoy stadii otkrytougol’noy glaukomy posle odnoetapnogo khirurgicheskogo lecheniya s implantatsiey dvukh raznykh implantatov Ex-press i Ologen]. Glaukoma: Sbornik nauchnykh statey XI mezhdunarodnogo kongressa, Moskva, 31-39
4. AstakhovSY, HarshaAA (2013). An effective method of surgical treatment of patients with refractory glaucoma with Ex-press filtering device [Effektivnyy metod khirurgicheskogo lecheniya bol’nykh refrakternoy glaukomoy s ispol’zovaniem fil’truyushchego ustroystva Ex-press]. Oftal’mologicheskie vedomosti, (1), 3-8
5. BikbovMM, AbsalyamovMS, KhusnitdinovII, Chayka OV, OrenburkinaOI, KhismatullinRR, ZainullinaNB(2012). Our experience with Ex-Press shunt surgery for glaucoma [Nash opyt primeneniya shunta Ex-Press v khirurgii glaukomy]. IX Vserossiyskaya shkola oftal’mologa: Sbornik nauchnykh statey, 37-39.
6. BikbovMM, BabushkinAE, ChaykaOV, Orenbur-kinaOI, KhusnitdinovII (2015). The effectiveness of the drainage surgery in refractory glaucoma [Ob effek-tivnosti drenazhnoy khirurgii pri refrakternoy glaukome]. Oftal’mologiya. Vostochnaya Evropa, (3), 81-86.
7. BikbovMM, SurkovаVK, KhusnitdinovII, Orenbur-kinaOI, KhismatullinRR, ChaykaOV (2014). The role of the Ahmed drainage surgery in refractory glaucoma [Rol’ drenazha Ahmed v khirurgii refrakternoy glaukomy]. Vostok-Zapad. Tochka zreniya: Sbornik nauchnykh statey, (1), 103-106.
8. BikbovMM, SurkovаVK, KhusnitdinovII, Orenbur-kinaOI, ChaykaOV (2014). Results of surgical treatment of refractory glaucoma with the use of collagen bio-drainage [Rezul’taty khirurgicheskogo lecheniya refrakternoy glaukomy s ispol’zovaniem kollagenovogo biodrenazha]. Oftal’mologiya, (2), 55-58.
9. BikbovMM, KhusnutdinovII (2015). Canaloplasty in patients with primary glaucoma oktrytougolnoy [Kanaloplastika u patsientov s pervichnoy oktrytougol’noy glaukomoy]. Vestnik OGU. Orenburg, (12), 35-37.
10. BikbovMM, KhusnitdinovII (2016). The results of combined surgery in patients with primary open angle glaucoma and complicated cataract with drain-age “Glauteks” [Rezul’taty kombinirovannogo khirur-gicheskogo vmeshatel’stva u bol’nykh s pervichnoy otkrytougol’noy glaukomoy i oslozhnennoy kataraktoy s ispol’zovaniem drenazha «Glauteks»]. Kataraktal’naya i refraktsionnaya khirurgiya, (1), 42-46.
11. VolkovaNV, YuryevaTN (2013). Morphogenesis of the outflow tract and evaluation of the hypotensive effect of the modified mini-shunt implantation Ex-Press [Morfogenez putey ottoka i otsenka gipotenzivnogo effekta modifitsirovannoy implantatsii mini-shunta Ex-Press]. Oftal’mokhirurgiya, (3), 66-71.
12. GavrilovIA, ChuprovAD (2011). The first experience of Ex-Press shunt surgery in refractory glaucoma [Pervyy opyt primeneniya shunta Ex-Press v khirurgii refrakternoy glaukomy]. «Glaukoma: teorii, tendentsii, tekhnologii»: Sbornik nauchnykh trudov 9-y konferentsii, 79-82.
13. EgorovEA (ed.) (2013). Glaucoma. National guidance [Glaukoma. Natsional’noe rukovodstvo], 824.
14. DzhumovaMF, MarchenkoLN, DzhumovaAA (2013). Comparison of the results of the implantation of drainage Ex-Press and trabeculectomy in primary glaucoma [Sravnenie rezul’tatov implantatsii drenazha Ex-PRESS i trabekulektomii pri pervichnoy glaukome]. Sbornik nauchnykh trudov, 50-56.
15. ErichevVP, ErmolaevAP (2008). Efficacy and safety of drainage surgery for neovascular glaucoma [Effektivnost’ i bezopasnost’ drenazhnoy khirurgii pri neovaskulyarnoy glaukome] Glaukoma: real’nost’ i perspektivy. Sbornik nauchnykh statey, 30-32.
16. KryachkoNS, PureskinNP, MigalSF, MigalDS (2015). The results of the application of the Ex-Press shunt and “Glauteks” drainage in treatment of secondary glaucoma [Rezul’taty primeneniya shunta Ex-Press i drenazha «Glauteks» v kompleksnom lechenii vtorichnoy glaukomy]. Novosti glaukomy, (1), 129-131.
17. KuroedovAV, OgorodnikovVY (2010). Microdrainage using the Ex-Press mini shunt as an option of surgical treatment of patients with primary open-angle glaucoma advanced stages of the disease [Mikrodrenirovanie s pomoshch’yu Ex-PRESS mini-shunta kak variant vybora operativnogo lecheniya patsientov s pervichnoy otkrytougol’noy glaukomoy prodvinutykh stadiy bolezni]. Oftal’mologiya, (1), 23-28.
18. KuroedovAV, OgorodnikovVY, FominNE (2015). The results of long-term monitoring of patients with primary open angle glaucoma after implantation of mini-shunt Ex-Press [Rezul’taty prodolzhitel’nogo nablyudeniya za patsientami s pervichnoy otkrytougol’noy glaukomoy posle implantatsii mini-shunta Ex-Press]. Klinicheskaya oftal’mologiya, (3), 131-136
19. KhusnitdinovII, BikbovMM (2015). Simultaneous cataract phacoemulsification with implantation of Ahmed valve in patients with refractory glaucoma [Odnomomentnaya fakoemul’sifikatsiya katarakty s implantatsiey klapana Ahmed u patsientov s refrakternoy glaukomoy]. Vestnik OGU. Orenburg, (12), 270-272
20. BikbovMM, KhusnitdinovII (2015). The results of the use of Ahmed valve in refractory glaucoma surgery. J. Curr. Glaucoma Pract., 9(3), 86-91.
21. BroadwayDC, GriersonI, HitchingsRA (1998). Local effects of previous conjunctival incional surgery and subsequent outcome of filtration surgery. Am. J. Ophthalmol., (125), 805-818.
22. CasiniG, LoiudiceP, MartinelliP, NasiniF, NardiM (2015). Malignant glaucoma-like syndrome after EX-PRESS filtration surgery. Eur. J. Ophthalmol., 25(4), 42-45.
23. CasiniG, LoiudiceP, PellegriniM, SframeliAT, MartinelliP, PassaniA, NardiM (2015). Trabeculectomy versus Ex-Press shunt versus Ahmed valve implant: short-term effects on corneal endothelial cells. Am. J. Ophthalmology, 160(6), 1185-1190
24. CherofAM, SooHooJR, KahookMY, SeiboldLK (2015). Endophthalmitis with corneal infiltrate after Ex-Press glaucoma drainage device implantation. Int. J. Ophthalmol., 8(3), 492-495.
25. CoupinA, LiQ, RissI (2007). Ex-PRESS miniature glaucoma implant inserted under a scleral flap in open-angle glaucoma surgery: a retrospective study. Fr. Ophtalmol., 30(1), 18-23.
26. DahanEL, Carmichael TR (2005). Implantation of a Miniature glaucoma device under a scleral flap. J. Glaucoma, 14(2), 98-102
27. De JongL, LafumaA, AguadéAS, BerdeauxG (2011). Five-year extension of a clinical trial comparing the EX-PRESS glaucoma filtration device and trabeculectomy in primary open-angle glaucoma. Clin. Ophthalmol., (5), 527-533
28. DreyerEB, DreyerRE (2014). Two cases of suprachoroidal hemorrhage after implanta-tion of an Ex-Press miniature glaucoma device and an intraocular lens. Ophthalmol. Med., (1-3), doi.org/10.1155/2014/294921.
29. GandolfiS, TraversoCF, BronA, SellemE,Kaplan-MessasA, BelkinM (2002). Short-term results of a miniature drainage implant for glaucoma in combined surgery with phacoemulsification. Acta Ophthalmol. Scand. Suppl., (236), 266
30. KannerEM, NetlandPA, SarkisianJr.SR, DuH (2009). Ex-PRESS miniature glaucoma device implanted under a scleral flap alone or combined with phacoemulsification cataract surgery. J. Glaucoma, 18(6), 488-491
31. KatoN, TakahashiG, KumegawaK, KabataY,TsuneokaH. (2015). Indications and postoperative treatment for Ex-PRESS(®) insertion in Japanese patients with glaucoma: comparison with standard trabeculectomy. Clin. Ophthalmol., 8(9), 1491-1498, doi:https://doi.org/10.2147/OPTH.S86504.
32. MabrayMC, UzelacA, TalbottJF, LinSC,GeanAD (2015). Ex-PRESS glaucoma filter: an MRI compatible metallic orbital foreign body imaged at 1.5 and 3T. Clin. Radiol., 70(5), 28-34. doi:https://doi.org/10.1016/j.crad.2015.01.010.
33. MarisPJ, Jr IshidaK, NetlandPA (2007). Comparison of trabeculectomy with Ex-PRESS miniature glaucoma device implanted under scleral flap. J. Glaucoma, (16), 14-19.
34. MendaSA, LowryEA, PorcoTC, StamperRL, RubinMR, HanY (2015). Ex-PRESS outcomes using mitomycin-C, Ologen alone, Ologen with 5-fluorouracil. Ophthalmol., 35(3), 357-363.
35. MermoudА (2005). Ex-PRESS implant. Br. J. Ophthalmol., (89), 396-397.
36. MincklerDS, FrancisBA, HodappEA, JampelHD, LinSC, SamplesJR, SmithSD, SinghK (2008). Aqueous shunts in glaucoma: a report by the American Academy of Ophthalmology. Ophthalmology, (115), 1089-1098.
37. NetlandP, RoyS (2007). Ex-PRESS shunt delivers good long term results. EuroTimes, 12(9), 36.
38. Pe’erJ, FolbergR, ItinA, GnessinH, HemoI, KeshetE (1998). Vascular endothelial growth factor upregulation in human central retinal vein occlusion. Ophthalmology, 105(3), 412-416.
39. TavolatoM, BabighianS, GalanA (2006).Spontaneous extrusion of a stainless steel glaucoma drainage implant (Ex-PRESS). J Ophthalmol., 16(5), 753-755.
40. TojoN, HayashiA, MiyakoshiA (2015). Corneal decompensation following surgery with the Ex-press nimi glaucoma shunt device. Clin. Ophtalmol., 17(9), 499-502.
41. WamsleyS, MosterMR, RaiS, AlvimHS, FontanarosaJ (2004). Results of the use of the Ex-PRESS miniature glaucoma implant in technically challenging, advanced glaucoma cases: a clinical pilot study. Am. J. Ophthalmol., 138(6), 1049-1051
42. YilmazGS, YildirimS, DegirmenciC, AtesH (2016).Evaluation of Ex-PRESS mini glaucoma shunt implantation with preoperative intracameral bevacizumab injection in refractory neovascular glaucoma. Eur. J. Ophthalmol., (Mar), 5, doi:https://doi.org/10.5301/ejo.5000763
