Possibility of application of micronuclear dough in a bukkal epithelium is considered when comparing chemical, radiation and combined radiochemical pollution of the environment. At the combined influence of a chemical and radiation factor by authors possible manifestation, both additive effects, and a sinergizm and inhibition is revealed. The conclusion is drawn that cytogenetic characteristics of a bukkal epithelium can be used as "the biological dosimeter" total level of environmental pollution.
environment, chemical pollution, radioactive pollution, combined pollution, bukkal epithelium, cytogenetic violations, micronuclear test.
1. Average effective doses of radiation accumulated in 1986-2001 for the population in settlement residents of the Russian Federation being in contaminated areas caused by the disaster at the Chernobyl nuclear power plant: Reference Book / under the editorship of G. Ya. Brukk. - M.: Ministry of Health of Russian Federation, 2002. - 206 p.
2. Byakhova, M. M. Karyological and immunological parameters in children under conditions of varying ambient air pollution / M. M. Byakhova, L. P. Sychev, V. S. Zhurkov [etc.] // Hygiene and sanitation. - 2010. - No. 3. - pp. 9-12.
3. State Report "On the State and Protection of the Environment in the Russian Federation in 2012". - M.: Ministry of Natural Resources and Environment of RF, 2013. - 483 p.
4. Dzhambetova, P. M. Assessment of influence of petroleum pollutions of soils on the cytogenetic status and indexes of apoptosis in the cells of buccal epithelium of children / P. M. Dzhambetova, L. G. Molochayeva, A. B. Makhtiyeva[etc.] // Ecological genetics. - 2009. - No. 4. - pp. 34-40.
5. Korsakov, A.V. Integral ecological hygienic assessment of environmental changes as a risk factor for human health: Monograph / A.V. Korsakov, V. P. Mikhalev, V. P. Troshin. - Palmarium Academic Publishing, 2012. - 404 p.
6. Korsakov, A.V. Influence of a complex of inhabitancy technogenic factors on the frequency of cytogenetic disorders in a buccal epithelium of children of younger school age / A.V. Korsakov, V. P. Troshin, V. P. Mikhalev [etc.] // Bulletin of Moscow University. Ser. XXIII, Anthropology. - 2012. - No. 1. - pp. 110-118.
7. Cities and areas of the Bryansk region (2000-2009): Proceedings / under the editorship of N. A. Muratova. - Bryansk: Bryansk-stat, 2010. - 845 p.
8. Onishchenko, G.G. Radiological and medical consequences of the disaster at the Chernobyl nuclear power plant in the Russian Federation / G.G. Onishchenko // Hygiene and sanitation. - 2007. - No. 4. - pp. 6-13.
9. Rakhmanin, YU.A. Modern directions of risk assessment methodology / Yu.A. Rakhmanin, S. M. Novikov, T. A. Shashina// Hygiene and sanitation. - 2007. - No. 3. - pp. 3-9.
10. Sycheva, L.P. Cytogenetic monitoring for assessment of safety of environmental health / L.P. Sycheva // Hygiene and sanitation. - 2012. - No. 6. - pp. 68 - 72.
11. Yablokov, A.V. Chemical and radiation pollution of the environment as major factors of additional global mortality in the XX century / A.V. Yablokov // Issues of biological medicine and pharmaceutical chemistry. - 2004. - No. 4. - pp. 9-11.
12. Stich, H.F. Towards an automized micronucleus assay as a internal dosimeter for carcinogen-exposed Human population groups / H.F. Stich, A.V. Acton, B. Palcic // Recent Results in Cancer Res. - 1990. - V. 120. - P. 94-108.
