High relative humidity of the air caused by frequent unfavourable weather (fog, flooding, daily fluctuations of temperature) is one of the triggers of bronchial constriction that significantly worsens the course of asthma and leads to the increased number of hospital admission. The people with osmotic airway hyperresponsiveness are expected to have the changes in the quality of life in the seasons of the year with high air humidity. The aim of the research was to reveal the features of general and specific quality of life of patients with osmotic airway hyperresponsiveness in contrast seasons of the year. 65 patients of asthma were examined with the questionnaires of SF-36, AQLQ, HADS. High frequency of anxious depression disorders in patients with osmotic hyperresponsiveness and the suppressive effect of anxiety on the low self-esteem of general and specific quality of life in this group in dry season were found. The dominating influence of high humidity on all aspects of quality of life was shown. In blight and humid period of the year the dependence of the majority of components of general and specific quality of life from each other is neutralized and the influence of anxiety on the self-esteem of health fully disappears.
asthma, quality of life, osmotic airway hyperresponsiveness, humidity, seasons of the year
1. Perelman N.L. Seasonal peculiarities of life quality in patients with bronchial asthma and cold airway hyperresponsiveness. Bûlleten´ fiziologii i patologii dyhaniâ 2009; 31:29−32 (in Russian).
2. Perelman N.L. Influence of emotional problems on quality of life in asthmatics with cold airway hyper reactivity. Dal´nevostochnyy meditsinskiy zhurnal 2009; 4:6-10 (in Russian).
3. Perelman N.L. Health-related quality of life in asthma patients with osmotic airway hyperresponsiveness. Bûlleten´ fiziologii i patologii dyhaniâ 2016: 59:16−20 (in Russian).
4. Perelman J.M. Immediate questions of ecological physiology of respiration. Bûlleten´ fiziologii i patologii dyhaniâ 2001; (8):20-26 (in Russian).
5. Perelman J.M., Prikhodko А.G. Spirographic diagnosis of disorders of pulmonary ventilation function: a guide for physicians. 2nd ed. Blagoveshchensk; 2013 (in Russian).
6. Prikhodko A.G. Respiratory tract response to hypoosmotic stimulus. Bûlleten´ fiziologii i patologii dyhaniâ 2005; 21:47-52 (in Russian).
7. Ul´yanychev N.V. Automated system for scientific studies in the area of physiology and pathology of respiration of man. Novosibirsk: Nauka; 1993 (in Russian).
8. Khizhnyak Yu.Yu., Perelman J.M., Kolosov V.P. Seasonal dynamics and cross-reactivity of the airways in patients with bronchial asthma in the conditions of climate. Tikhookeanskiy meditsinskiy zhurnal 2009; (1):82-84 (in Russian).
9. García-Marcos L., Carvajal-Urueña I., Escribano-Montaner A., Fernández-Benítez M., García de la Rubia S., Tauler Toro E., Pérez-Fernández V., Barcina-Sánchez C. Seasons and other factors affecting the quality of life of asthmatic children. J. Investig. Allergol. Clin. Immunol. 2007; 17(4):249−256.
10. Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention (Updated 2016). Available at: www.ginasthma.com.
11. Juniper E.F., Buist A.S., Cox F.M., Ferrie P.J., King D.R. Validation of a standardized version of the Asthma Quality of Life Questionnaire. Chest 1999; 115:1265−1270.
12. Lavoie K.L., Bacon S.L., Barone S., Cartier A., Ditto B., Labrecque M. What is worse for asthma control and quality of life: depressive disorders, anxiety disorders, or both? Chest 2006; 130(4):1039−1047.
13. Perelman N.L. Seasonal differences of quality of life in asthmatics with cold airway hyperresponsiveness. Eur. Respir. J. 2009; 34(S53):551.
14. Puhan M.A., Frey M., Büchi S., Schünemann H.J. The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease. Health Qual. Life Outcomes 2008; 6:46. doi:https://doi.org/10.1186/1477-7525-6-46.
15. Ware J.E. SF-36 Health Survey. Manual and interpretation guide. Second printing. Boston: The Health Institute, New England Medical Center; 1997.
16. Zigmond A.S., Snaith R.P. The hospital anxiety and depression scale. Acta Psychiatr. Scand. 1983; 67(6):361−370.
