The article presents the results of serum enzymes study in endurance sports. 311 elite athletes were investigated in swimming, biathlon, cycling, cross country skiing, rowing and kayaking. Capillary blood examination was performed on training camps during ten years. We included in statistical analysis 6950 CK tests, 5904 - AST and 5667- ALT. They were analyzed depending on kind of sport, training stage preparation and gender. The physiological serum enzyme ranges of elite athletes were estimated in view of sport, gender differences and stage of preparation. Serum enzyme activity trend was found in endurance sports at various preparation stages of the annual cycle of training. The high individual variation of CK activity was in endurance sports (variation coefficient 65,0-102,9% for men and 44,0-128,8% for women). It revealed the significantly higher CK activity in men compared to women. The trend of CK activity decrease was found from preparatory to competitive period. We examined the excess frequency enzyme activity higher upper limit of reference ranges for healthy individuals. It was 29,0% for CK, 23,2% - AST and 9,3% - ALT.
serum enzymes, endurance sports, sports biochemistry, laboratory monitoring.
1. Makarova G.A., Loktev S.A. Meditsinskiy spravochnik trenera. M.: Sovetskiy sport. 2005. 587 s.
2. Shirkovets E.A., Titlov A.Yu., Lun´kov S.M. Kriterii i mekhanizmy upravleniya podgotovkoĭ sportsmenov v tsiklicheskikh vidakh sporta. Vestnik sportivnoy nauki. 2013. № 5. S. 44-48.
3. Banfi G., Colombini A., Lombardi G., Lubkowska A. Metabolic markers in sports medicine. Adv. Clin. Chem. 2012. № 56. P. 1-54.
4. Brancaccio P., Lippi G., Mafulli N. Biochemical markers of muscular damage. Clinical Chemistry and Laboratory Medicine. 2010. № 48(6). R. 757-767.
5. Brancaccio P., Maffulli N., Buonauro R., Limongelli F.M. Serum enzyme monitoring in sports medi-cine. Clin. Sports Med. 2008. № 27 (1). P. 1-18.
6. Chen T.C., Lin K.Y., Chen H.L., Lin M.J, Nosaka K. Comparison in eccentric exercise-induced muscle damage among four limb muscles. European Journal of Applied Physiology. 2011. №111. R. 211-223.
7. Gleeson M. Biochemical and immunological markers of overtraining. Journal of Sport Science and Medicine. 2002. № 1. P. 31-41.
8. Jamurtas A.Z., Theocharis V., Tofas T., Tsiokanos A., Yfanti C., Paschalis V., Koutedakis Y., Nosa-ka K. Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. European Journal of Applied Physiology. 2005. № 95. R. 179-185.
9. Machado M., Brown L. E., Augusto-Silva P., Pereira R. Is exercise-induced muscle damage susceptibility body segment dependent? Evidence for whole body susceptibility . J Musculoskelet Neuronal Interact. 2013. № 13. P. 105-110.
10. Machado M., Willardson J.M., Silva D.P., Frigulha I.C., Koch A.J., Souza S.C. Creatine Kinase Activity Weakly Correlates to Volume Completed Following Upper Body Resistance Exercise. Res Q Exerc Sport. 2012. № 83. P. 276-281.
11. Nosaka K., Clarkson P.M. Relationship between post-exercise plasma CK elevation and muscle mass involved in the exercise. Int J Sports Med. 1992. № 13. P. 471-475.
12. Saka T., Bedrettin A., Yazici Z., Sekir U., Gur H., Ozarda Y. Differences in the magnitude of muscle damage between elbow flexors and knee extensors eccentric exercises. J Sports Sci Med. 2009. № 8. P. 107-115.
13. Tiidus P.M. Influence of estrogen on muscle plasticity. Braz. J. Biomotricity. 2011. № 4. P. 143-155.



