The implementation of the national project "Safe and High-quality Highways" is aimed at spreading the successful experience of using innovative materials, structures and technological solutions for federal projects at road facilities of regional and inter-municipal subordination. There are no approaches to evaluate the economic efficiency of using new and best technologies for the objects of regional subordination or they are not provided with a methodological basis for evaluating their total economic profitability. The objective of the research conducted by the group of authors is to develop methods to prove the efficiency of a wide range of innovations for objects of regional subordination. The research problem is to study the issues of effective transfer to the subjects of the Russian Federation of technological solutions used in construction and repair work on federal highways. This is due not only to the lack of experience in the application of innovations, the high cost of new production and laboratory equipment for their implementation, the small scale of the work carried out, but also significantly different operating conditions, maintenance of these road facilities. In this part of a comprehensive study conducted within the framework of the federal project "System-wide Measures for the Development of Road Facilities", the authors propose a methodological approach to calculating the efficiency of using polymer-bitumen binders. Cost-effectiveness analysis for arrangement of polymer-asphalt-concrete coatings on highways was used as the methodological basis for evaluating the economic efficiency of applying this technological solution.