TY CONF TI The development of original methodologies of directed synthesis of le-Carbs their analogs and precursors base donacetylene and its derivatives KW acetylene and its derivatives KW nitrogen-containing heterocycles KW nucleophiles KW zwitter-ions KW atom-economic addition reactions KW drug precursors JO Topical issues of translational medicine: a collection of articles dedicated to the 5th anniversary of the day The creation of a department for biomedical research and technology of the Irkutsk Scientific Center Siberian Branch of RAS AU Trofimov, B.A. AU Gusarova, N.K. PY 2024 PB INFRA-M Academic Publishing LLC.