%0 Conference Article %T The development of original methodologies of directed synthesis of le-Carbs their analogs and precursors base donacetylene and its derivatives %A Trofimov, B.A. %A Gusarova, N.K. %K acetylene and its derivatives, nitrogen-containing heterocycles, nucleophiles, zwitter-ions, atom-economic addition reactions, drug precursors %J Topical issues of translational medicine: a collection of articles dedicated to the 5th anniversary of the day The creation of a department for biomedical research and technology of the Irkutsk Scientific Center Siberian Branch of RAS %D 2024 %P 4 %I INFRA-M Academic Publishing LLC.