Russian Federation
Russian Federation
Russian Federation
Russian Federation
Russian Federation
Russian Federation
The purpose of the study is to show the expediency of sequentially extracting herbal medicinal raw mate-rials with solvents in order of increasing their polarity, to reveal the nature of the distribution of both different groups of compounds and individual ones in the organic matter of thyme (thyme creeping). Re-sults and their discussion. The results of comparative characterization of the chemical composition and direction of pharmacological action of n-hexane, choroform and ethanol extracts of sequential exhaustive extraction of thyme herb (creeping thyme) obtained using chromatography-mass spectrometry, mass spectra and structural formulas of individual compounds, which were identified in 162 (n-hexane), 101 (chloroform) and 150 (ethanol) extracts. The influence of the nature of the solvent on both the yield of extracts and the structural and group composition of the latter, the features of the structural organization of the extracted compounds have been established, the specificity of the direction of the pharmacologi-cal action of each of the extracts, which made it possible to justify the expediency of successive exhaustive extraction of the initial medicinal raw materials with solvents in ascending order of their polarity.
thyme, extraction, mass spectrometry.
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