Tritium Organic Compounds in the Environment and Human Organism
Abstract and keywords
Abstract (English):
Purpose: To evaluate the ratio of tritium oxide and tritium organic compounds in the environment and in the body in order to justify the graded approach when calculating the dose for the personnel working in the presence of tritium and its compounds in the air of the working area. Material and methods: The study covered the forms of tritium (HTO and OBT) in water, air and bodies of the personnel working under conditions of the presence of tritium and its compounds in the air of the working area. Samples of water, air and biological assays (urine) of the personnel were collected for the study. Sample preparation of the collected material was carried out according to the approved methods certified by the Federal State Unitary Enterprise “VNIIFTRI”. The liquid scintillation alpha-beta spectrometer Tri-Carb 3180TR/SL was used when estimating tritium concentrations in the preformed samples. Results: It has been established that in the environment (water and air) and under the industrial conditions (air of the working area), tritium is to a greater extent in the form of OBT, which determines its predominant intake into the body of the personnel in the form of OBT. The ratio of tritium forms in biological fluids (urine) of the personnel was estimated using three methods. It was shown that OBT in the body of the personnel accounted for 70 to 90 %. These data indicate that OBT in the body of the personnel accounts for a larger share in comparison with HTO, therefore, the dose assessments of the personnel when working with tritium and its compounds should be revised. Conclusion: Taking into account the developed methods for the separation of tritium oxide and its organic forms, the assessment of the dose induced by tritium exposure should be performed gradually, taking into account the ratio of these forms in the body of the particular worker.

Keywords:
radiation safety, tritium, tritium oxide, organically bound tritium compounds, HTO/OBT ratio, water, air, personnel
References

1. Kochetkov OA, Monastyrskaya SG, Kabanov DI Problemy normirovaniya tehnogennogo tritiya (obzor). Saratovskiy nauchno-medicinskiy zhurnal. 2013; 9(4): 815 - 819 [Kochetkov OA, Monastyrskaya SG, Kabanov DI Problems of anthropogenic tritium limitation (review). Saratov Journal of Medical Scientific Research. 2013; 9(4): 815 - 819 (In Russian)]

2. Sources and Effects of Ionizing Radiation. UNSCEAR 2016 Report. Report to the General Assembly. Annex C. Biological effects of selected internal emitters -Tritium. United Nations Scientific Committee on the Effects of Atomic Radiation. United Nations, New York, 2016.

3. Diabate S, Strack S. Organically bound tritium. Health Phys, 1993, 65(6): 698-712

4. Rochalska M, Szot Z. The incorporation of organically-bound tritium of food into some organs of the rat. Int J Radiat Biol Relat Stud Phys Chem Med, 1977, 31(4): 391-5

5. Saito M, Ishida MR, Travis CC. Dose-modification factor for accumulated dose to cell nucleus due to protein-bound 3H. Health Phys 1989, 56(6): 869-74

6. Kim SB, Baglan N, Davis PA. Current understanding of organically bound tritium (OBT) in the environment. J Environ Radioact 2013; 126: 83-91

7. Balonov MI Tritium dosimetry and standardization Ehnergoatomizdat 1983.

8. Balonov MI, Muksinova KN, Mushkacheva GS.Tritium radiobiological effects in mammals: review of experiments of the last decade in Russia. Health Phys. 1993; 65(6): 713-26.

9. ICRP. Age-dependent doses to members of the public from intake of radionuclides: Part 1. ICRP Publication 56. Annals of the ICRP, 1990; 20(2).

10. ICRP. Age-dependent doses to members of the public from intake of radionuclides: Part 2. Ingestion dose coefficients. ICRP Publication 67. Annals of the ICRP. 1993; 23(3-4).

11. Metodicheskie ukazaniya po metodam kontrolya. MUK 4.3. 044 -2012. Metodika opredeleniya ob'emnoy aktivnosti organicheskih i neorganicheskih soedineniy tritiya v vodnyh ob'ektah metodom zhidkoscintillyacionnoy spektrometrii. Attestovana FGUP «VNIIFTRI». Svidetel'stvo ob attestacii metodiki radiacionnogo kontrolya №40090.2V370 ot 20 marta 2012 goda

12. MUK Metodika opredeleniya koncentracii organicheskih i neorganicheskih soedineniy tritiya v vozduhe okruzhayuschey sredy i proizvodstvennyh pomescheniy MUK 4.3.047-2017. Metodika attestovana FGUP «VNIIFTRI». Svidetel'stvo ob attestacii № 45063.16326/ RA. RU. 311243-2015 ot 5 maya 2016 goda.

13. ICRP. Limits for intakes of radionuclides by workers. ICRP Publication 30 (Part 3). Ann ICRP, 1981; 6 (2-3).

14. ICRP, 2016. Occupational Intakes of Radionuclides: Part 2. ICRP Publication 134. Ann. ICRP, 2016; 45(3/4), 1-352.

15. Vorob'eva NYu, Kochetkov OA, Pustovalova MV i dr. Sravnitel'nye issledovaniya obrazovaniya fokusov γN2AH v mezenhimnyh stvolovyh kletkah cheloveka pri vozdeystvii 3N-timidina, oksida tritiya i rentgenovskogo izlucheniya. Kletochnye tehnologii v biologii i medicine, 2018;(3):205-8. [Vorobyeva NYu, Kochetkov OA, Pustovalova MV, Grehova AK,Blohina TM, Yashkina EI, et al. Comparative study of γH2AX foci formation in human mesenchymal stem cells exposed to 3H-thymidine, tritium oxide and X-rays. Cell Technologies in Biology and Medicine. 2018;3:205-8. (in Russ.)]

16. Pointurier F, Baglan N, Alanic G, Chiappini R. Determination of organically bound tritium backeground level in biological samples from a wide area in the south-west of France. J Environ Radioactivity. 2003; 68:171-189.

17. Baglan N, Kim SB, Cossonnet C, Croudace IW, Fournier M, Galeriu D. et al. Organically bound tritium (OBT) behaviour and analysis: outcomes of the seminar held in Balaruc-les-Bains in May 2012. Radioprotection 2013; 48(1):127-44

18. Kabanov DI, Kochetkov OA, Fomin GV, Vayzer VI, Veselov VM. K obosnovaniyu kontrolya organicheski svyazannogo tritiya v okruzhayuschey srede yadernyh ustanovok. Voprosy atomnoy nauki i tehniki. Ser. Termoyadernyy sintez, 2012; (1):17-22. [Kabanov DI, Kochetkov OA, Fomin1 GV, Vaizer VI, Veselov VM To justification of organically bound tritium monitoring in nuclear facilities environment. Problems of atomic science andtechnology Series thermonuclear fusion. 2012; (1):17-22. DOI:https://doi.org/10.21517/0202-3822-2012-35-1-17-22 ]

19. Metodika MT 1.2.1.15.002.0238-2014 «Vypolnenie izmereniy pri radiacionnom kontrole tritiya i ugleroda-14 v pomescheniyah AES s primeneniem rashodomera-probootbornika TASC-HT-HTO-C14 (MVK). Attestovana FGUP «VNIIFTRI». Svidetel'stvo ob attestacii №40063.4D199/01.00294-2010 ot 14 maya 2014 goda. Zaregistrirovana v Federal'nom informacionnom fonde po OEI № F.1.40.2014.18213.

20. Tritiy i ego soedineniya. Kontrol' velichiny individual'noy effektivnoy dozy vnutrennego oblucheniya pri postuplenii v organizm cheloveka.

21. Rukovodstvo pol'zovaniya priborom Tri-Carb 3180 TR/SL.

22. Rukovodstvo pol'zovaniya priborom Pyrolyser-6 Trio

23. Mezhgosudarstvennyy standart GOST 31861-2012. «Voda Obschie trebovaniya k otboru prob». 2014 g.

Login or Create
* Forgot password?