Tula, Russian Federation
Tula, Tula, Russian Federation
Tula, Tula, Russian Federation
Gemorragicheskaya lihoradka s pochechnym sindromom (GLPS) odno iz aktual'nyh prirodno-ochagovyh virusnyh zabolevaniy Rossiyskoy Federacii. Eto ostroe virusnoe zabolevanie s aerogennym mehanizmom peredachi vozbuditelya, harakterizuyuscheesya sistemnym porazheniem melkih sosudov, gemorragicheskim diatezom, gemodinamicheskimi rasstroystvami i porazheniem pochek. GLPS otnositsya k zoonozam s prirodnoy ochagovost'yu. Vozbuditelyami GLPS v Rossii yavlyayutsya 6 hantavirusov: Puumala, Kurkino i Sochi — v evropeyskoy chasti, Hantaan, Amur i Seul — na Dal'nem Vostoke. Prirodnymi hozyaevami hantavirusov i istochnikom zarazheniya lyudey GLPS yavlyayutsya dikie gryzuny. Suschestvuet pryamaya zavisimost' zabolevaemosti cheloveka gemorragicheskoy lihoradkoy s pochechnym sindromom ot chislennosti gryzunov i ih inficirovannosti na territorii, a takzhe ot ob'ema i kachestva deratizacionnyh rabot, provodimyh dlya profilaktiki i snizheniya zabolevaniya. Nachinaya s 1978 g., kogda byla vvedena oficial'naya registra- ciya zabolevaemosti GLPS MZ RF, po 2016 g. vklyuchitel'no zaregistrirovano bolee 245 tys. klinicheski diagnostirovannyh sluchaev GLPS. V dannom obzore rassmatrivayutsya naibolee vstrechaemye vozbuditeli dannogo zabolevaniya, osnovnye zven'ya patogeneza, klinicheskie proyavleniya i osobennosti ih techeniya u vzroslyh.
hantavirus, GLPS, gemorragicheskiy sindrom.
1. Alekseev O.A., Suzdal'cev A.A., Efratova E.S. Immunnye mehanizmy v patogeneze gemorragicheskoy lihoradki s pochechnym sindromom.// Ter. Arhiv. - 1998. - №11. S.39-42.
2. Bashkirev T.A. Klinicheskaya shema patogeneza gemorragicheskoy lihoradki s pochechnym sindromom v Srednem Povolzh'e. Sb. nauch. trudov. - L., 1980. - S.50-55.
3. Valishin D.A., Rabinovich V.I., Murzabaeva R.T., Mamon A.P., Murzagaleeva L.V //Sovremennoe predstavlenie o patogeneze gemorragicheskoy lihoradki s pochechnym // Medicinskiy vestnik Bashkortostana, 2008.-N 3.-S.57-62.
4. Galieva A.T. Infekcionno-toksicheskiy shok v klinike gemorragicheskoy lihoradki s pochechnym sindromom / Medicinskiy vestnik Bashkortostana. - 2009. - T. 4. №3. S. 14-17.
5. Dzagurova T.K., Tkachenko E.A., Yunicheva Yu.V. i dr. Obnaruzhenie i kliniko-etiologicheskaya harakteristika GLPS v subtropicheskoy zone Krasnodarskogo kraya. ZhMEI, 2008, S. 12-16.
6. Matveeva I.B. Immunologicheskie i patomorfologicheskie aspekty patogeneza gemorragicheskoy lihoradki s pochechnym sindromom. Materialy Vserossiyskoe nauchno - prakticheskoy konferencii «Gemorragicheskaya lihoradka s pochechnym sindromom: istoriya izucheniya i sovremennoe sostoyanie epidemiologii, patogeneza, diagnostiki, lecheniya i profilaktiki». - Ufa, 2006. S. 58-64.
7. Morozov V.G., Yunicheva Yu.V., Bryuhanov A.F., Slyusareva G.P., Roschupkin V.I., Tkachenko E.A. i dr. Sravnitel'naya harakteristika gemorragicheskoy lihoradki s pochechnym sindromom, vyzyvaemoy hantavirusami Puumala i Dobrava. Medicinskiy vestnik Severnogo Kavkaza, 2007, 2(6): S. 38-44.
8. Muhametdinova G.A., Fazlyeva R.M., Mustafina V.H., Dzagurova T.K. Kliniko-epidemiologicheskaya harakteristika gemorragicheskoy lihoradki s pochechnym sindromom v endemichnom regione. Epidemiologiya i infekcionnye bolezni, 2011, 1: S. 41-44.
9. Muhametdinova G.A., Fazlyeva R.M., Mustafina V.H., Dzagurova T.K. Kliniko-epidemiologicheskaya harakteristika gemorragicheskoy lihoradki s pochechnym sindromom v endemichnom regione. Epidemiologiya i infekcionnye bolezni, 2011, S. 41-44.
10. Roschupkin V.I., Suzdal'cev A.A. Gemorragicheskaya lihoradka s pochechnym sindromom. Saratov: Izd-vo Saratovskogo universiteta, Kuybyshevskiy filial, 1990.152 s.
11. Sirotin B.Z., Zharskiy S.L., Tkachenko E.A. Gemorragicheskaya lihoradka s pochechnym sindromom. Habarovsk: Izd-vo «RIOTIP»,2002. S. 26-31
12. Slonova R.A.,Tkachenko E.A., Ivanis V.A., Kompanec G.G., Dzagurova T.K. Gemorragicheskaya lihoradka s pochechnym sindromom (sovremennye aspekty ekologii, etiologii, epidemiologii, immunopatogeneza, diagnostiki, kliniki i lecheniya). Vladivostok: Izd-vo OAO «Primpoligrafkombinat», 2006 g. S. 35-37.
13. Suzdal'cev A.A., Roschupkin V.I., Morozov V.G. Reabilitaciya i dispanserizaciya bol'nyh gemorragicheskoy lihoradkoy s pochechnym sindromom. Uchebno-metodicheskoe posobie, Samara, 1999.
14. Tkachenko E.A., Dzagurova T.K., Ishmuhametov A.A., Morozov V.G, Gorodin V.N., Sockova S.E. Gemorragicheskaya lihoradka s pochechnym sindromom (istoriya, problemy i perspektivy izucheniya). 2016, S. 23-34.
15. Tkachenko E.A., Bernshteyn A.D., Dzagurova T.K., Morozov V.G., Slonova R.A., Ivanov L.I. i dr. Aktual'nye problemy sovremennogo etapa izucheniya gemorragicheskoy lihoradki s pochechnym sindromom v Rossii. ZhMEI, 2013,S. 51-58.
16. Tkachenko E.A., Dzagurova T.K., Ishmuhametov A.A., Morozov V.G.,Gorodin V.N., Sockova S.E. i dr. Gemorragicheskaya lihoradka s pochechnym sindromom (istoriya, problemy i perspektivy izucheniya).Epidemiologiya i vakcinoprofilaktika, 2016, 3: 23-34.
17. Fazlyeva R.M., Hunafina D.H., Kamilov F.H. Gemorragicheskaya lihoradka s pochechnym sindromom.Ufa, 1995. S. 242.
18. Hunafina, D.H. Gemorragicheskaya lihoradka s pochechnym sindromom: voprosy ranney klinicheskoy diagnostiki i dogospital'noy terapii / D.H. Hunafina, A.T Galieva, L.R. Shayhullina // Medicinskiy vestnik Bashkortostana. - 2008. - T. 3. - № 6.S. 40-44.9. Hunafina, D.H.
19. Jokinen E., Landevirta J., Collan V. Nephropathia epidemica: immunohistochemical study of pathogenesis. Clin. Nephrol 1978;V.59, №1, pp.1-5.
20. Dzagurova, T.K. Molecular diagnostics of hemorrhagic fever with renal syndrome during a Dobrava virus outbreak in the European part of Russia / T.K. Dzagurova, B. Klempa, G.P. Slusareva // J Clin Microbiol. 2009. - V. 47. - № 12. - P. 4029-4036.
21. Wichmann D., Slenczka W., Alter P. et al. Hémorragie fever with renal syndrome: diagnostic problems with a know disease. J. Clin. Microbiol., 2001. 39 (9). R. 3414-3416.