THE RELATIONSHIP BETWEEN DEPRESSION AND CARDIOVASCULAR DISEASE (REVIEW OF LITERATURE)
Abstract and keywords
Abstract (English):
Stat'ya posvyaschena aktual'noy probleme v oblasti konsul'tativnoy psihiatrii – komorbidnym depressivnym rasstroystvam u pacientov s serdechno-sosudistymi zabolevaniyami. Depressiya shiroko rasprostranena sredi kardiologicheskih pacientov. Primerno 31-45% pacientov s ishemicheskoy bolezn'yu serdca, vklyuchaya pacientov so stenokardiey napryazheniya, nestabil'noy stenokardiey ili infarktom miokarda, stradayut ot klinicheski vyrazhennyh simptomov depressii. Bolee togo, u 20 % pacientov s ishemicheskoy bolezn'yu serdca psihicheskie narusheniya sootvetstvuyut kriteriyam bol'shogo depressivnogo rasstroystva. Pacienty s hronicheskoy serdechnoy nedostatochnost'yu, mercatel'noy aritmiey i implantirovannym kardioverterom-defibrillyatorom takzhe nahodyatsya v gruppe povyshennogo riska razvitiya depressivnyh sostoyaniy. Depressiya ne prosto yavlyaetsya rasprostranennym sputnikom serdechno-sosudistyh zabolevaniy, no i okazyvaet negativnoe vozdeystvie na razlichnye aspekty techeniya zabolevaniya, vklyuchaya kachestvo zhizni, chastotu gospitalizaciy, obrascheniy za medicinskoy pomosch'yu i uroven' smertnosti. V stat'e predstavlen obzor literaturnyh istochnikov, posvyaschennyh fiziologicheskim mehanizmam vzaimosvyazi depressii i kardiologicheskih zabolevaniy. Depressiya i kardiologicheskie zabolevaniya imeyut dvunapravlennuyu svyaz', v kotoroy vospalitel'nye processy, endotelial'naya disfunkciya, povyshennaya aktivnost' trombocitov, disfunkcii neyrogumoral'noy i vegetativnoy nervnoy sistemy, otnosyaschiesya k depressii, i depressivnoe povedenie vzaimno potenciruyut drug druga. Nesmotrya na suschestvovanie effektivnyh i bezopasnyh metodov lecheniya depressii u pacientov s kardiologicheskimi zabolevaniyami, ee chasto nedoocenivayut i ne lechat. Sovmestnye medicinskie programmy – odin iz putey sovershenstvovaniya vyyavleniya i lecheniya depressii u kardiologicheskih pacientov. Neobhodimo provedenie dal'neyshih issledovaniy v etoy oblasti s uchastiem vrachey – kardiologov i psihiatrov.

Keywords:
depressiya, kardiovaskulyarnye zabolevaniya, neblagopriyatnye kardiologicheskie ishody.
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References

1. Spislit depressiya i serdce

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