Chita, Chita, Russian Federation
Proveden analiz DNK u 300 bol'nyh hronicheskim srednim otitom i 100 zdorovyh lic na nalichie variantov genotipov genov IL-1b 511T/S, IL-1b 31T/C, IL-10 1082G/A, IL-10 819S/T. Kombinaciya variantov genov IL- 1b 511T/S, IL-10 1082A/A, IL-10 819S/S, IL-1b 31C/C vstrechalas' u 57,8 % pacientov s epitimpanitom, v 35,7 % sluchaev vyyavleno nositel'stvo genov IL-1b 511T/T, IL-10 1082A/A, IL-10 819S/S, IL-1b 31T/C i IL-1b 511T/T, IL-10 1082A/A, IL-10 819S/S, IL-1b 31C/C. Sochetanie IL-1b 511T/T, IL-10 1082G/A, IL-10 819S/T, IL-1b 31T/C nablyudalos' v 46 % sluchaev mezotimpanita.
polimorfizm genov, hronicheskiy gnoynyy sredniy otit, prognozirovanie
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