The authors proposed and evaluated options of optimization of the algebraic model of constructive logic, designed to construct multichannel non-linear mathematical model often used in Russia in the in-depth analysis in medicine and biology. In the basis of optimization of this model are procedures for finding duplicate cases (rows base), relevant to the achievement of goals, and excluding those resulting components that are duplicated other cases the resulting components. Procedures for reviewing the results of the components of a top-down or bottom-up and comparing the numbers corresponding to achievement of objectives are the basis of optimization. If all the numbers viewing the resulting component will be present in other watched the resulting components, then it is removed as redundant. As a result of identifying and eliminating redundant coatings target lines are reducing the number of resulting parts. Reduction of number of resulting components is achieved by identifying and eliminating redundant coatings target lines. The results of two variants of optimization of mathematical model are shown on the example of the mathematical model identification features of the method of oxygen therapy in the treatment of oncological pathology. The authors suggested the possibility of practical use of various optimization algorithms to choose model with a minimal number of components of the resulting/