PECULIARITIES OF TOPOGRAPHIC ANATOMY AND CRYPT COMPARTMENT OF DISTAL COLON IN WISTAR RATS
Abstract and keywords
Abstract (English):
We studied distal colon of Wistar rats including descending transverse colon and rectum. Feature of distal colon in the left flexure are short mesenterium growing in size towards rectum, common mesenterium with small intestine attached to it on the right side and ligament forming left flexure and attached to it on the left side. It was found that one of the variants of normal blood supply is the absence of a. mesenterica caudalis. In this case blood supply comes from arterial arch formed by a. rectalis media and a. colica media. Moreover, in the classic variant of blood supply we revealed a variation in the amount of straight branches that go to this segment of colon wall from left colic and superior rectal arteries (from 3 to 5 from each artery). The structural features of rectum is weak expression of rectal ampulla that causes the depletion of fecal masses immediately after passing into rectum. Crypt compartment of colon of Wistar rats consists by 80,6 % of obligatory flora represented with Bacteroides ssp., Lactobacillus spp., Bifidobacterium spp., Enterococcus faecalis, E. coli (lac+), Grampositive rods. Facultative flora is represented with Proteus mirabilis, Peptococcus spp., Candida spp., Staphylococcus epidermidis, Citrobacter freundii and makes 19,4 %.

Keywords:
anatomy, rat, intestine, microflora
References

1. Belousova EA (2002). Ulcerative colitis and Crohn’s disease [Yazvennyy kolit i bolezn’ Krona], 128.

2. Vorobyov GI, Khalif IL (2008). Nonspecific inflammatory diseases [Nespetsificheskie vospalitel’nye zabolevaniya], 400.

3. Lepekhova SA (2012). Algorithm of standard surgical procedures: laboratory animals (admission, management and health control of animals in vivarium of a medical institution): teaching guide [Programma standartnykh operatsionnykh protsedur: laboratornye zhivotnye (priem, soderzhanie, ukhod i kontrol’ zdorov’ya zhivotnykh v vivariyakh meditsinskogo uchrezhdeniya): ucheb. posobie], 96.

4. Loranskaya ID, Boldyreva MN, Trofimov DY, Lavrentieva OA (2013). Abdominal and mucosa-associated microbiota of rectum at the irritable bowel syndrome [Polostnaya i pristenochnaya mikrobiota pryamoy kishki pri sindrome razdrazhennogo kishechnika], 69-74.

5. Nozdrachyov AD, Polyakov EL (2001). Anatomy of a rat (laboratory animals) [Anatomiya krysy (laboratornye zhivotnye)], 464.

6. Patient management protocol. Intestinal dysbacteriosis. OST 91500.11.0004-2003: Order of Public Health Ministry of the Russian Federation N 231 d.d. 09.06.2003 [Protokol vedeniya bol’nykh. Disbakterioz kishechnika. OST 91500.11.0004-2003: Prikaz MZ RF № 231 ot 09.06.2003].

7. Putnikov AV, Golota YV, Sergiychuk TM, Ostapchuk AM, Zakordonets LV, Ostapchenko LI, Tolstanova GM (2015). Quantitative and qualitative indices of rats’ intestinal microbiota [Kolichestvennye i kachestvennyy pokazateli kishechnoy mikrobioty krys]. Mikrobiologiya i biotekhnologiya, (2), 89-100.

8. Spreys IF, Alfyorova MA, Mikhalevich IM, Rozhkova NY (2006). Basics of applied statistics (using Excel and Statistica in medical researches): teaching guide [Osnovy prikladnoy statistiki (ispol’zovanie Excel i Statistica v meditsinskikh issledovaniyakh): ucheb. posobie], 71.

9. Tkachyov AV (2012). Inflammatory bowel diseases: at the intersection of the problems [Vospalitel’nye zabolevaniya kishechnika: na perekrestke problem]. Prakticheskaya meditsina, (3), 17-22.

Login or Create
* Forgot password?